Myeloproliferative Disorders

	Tweet

The myeloproliferative disorders are a group of diseases characterized by excessive proliferation of the myeloid elements secondary to a defect in the hematopoietic stem cell. As discussed earlier, the myeloid elements consist of erythrocytes, platelets, and the granulocytes, and there are disorders associated with the proliferation of each of these lines. These diseases are chronic in nature but tend to culminate in a more acute picture, such as acute leukemia. We consider four clinical expressions of the myeloproliferative disorders:

1. Chronic myelogenous leukemia (CML), with a predominant increase in the granulocytes
2. Polycythemia vera (PV), with a predominant increase in the red cells
3. Essential thrombocythemia (ET), with a predominant increase in the platelets
4. Myeloid metaplasia with myelofibrosis (MMMF), with a progressive fibrosis of the bone marrow with relocation of hematopoietic tissues to extramedullary sites

RELATED STORIES:
Essential Thrombocythemia   Amyloidosis   Plasma Cell Dyscrasias   Monoclonal Gammopathy of Uncertain Significance   Multiple Myeloma   Malignant Lymphomas   Non-Hodgkin’s Lymphomas   Myeloid Metaplasia with Myelofibrosis (MMMF)   Waldenstrom’s Macroglobulinemia   Hairy Cell Leukemia   Chronic Lymphocytic Leukemia   Acute Leukemias   Hodgkin’s Disease   Myelodysplasia   Chronic Myelogenous Leukemia   Polycythemia Vera

Comments

[ + Post Your Own ]

Now you're in the public comment zone. What follows is not Armenian Medical Network's stuff; it comes from other people and we don't vouch for it. A reminder: By using this Web site you agree to accept our Terms of Service. Click here to read the Rules of Engagement.

There are no comments for this entry yet. [ + Comment here + ]