Peripheral arterial disease (PAD) involves the atherosclerotic occlusion of the arterial circulation to the lower extremities. The disease may be asymptomatic (identified only by a reduced blood pressure in the ankle), or it may manifest symptoms of intermittent claudication or severe chronic leg ischemia. The typical patient with PAD presents a decade later than the patient with coronary artery disease and experiences a profound limitation in exercise capacity and quality of life.
In addition to affecting the limbs, PAD is a manifestation of systemic atherosclerosis affecting other major circulations involving the cerebral and coronary circulations. Thus, all patients with PAD are at an increased risk of cardiovascular morbidity and mortality. The treatment goals are directed at providing symptom relief and at reducing the risk of systemic cardiovascular morbidity and mortality ... more » »
Raynaud's syndrome is an episodic vasospastic disorder characterized by digital color change (white-blue-red) with exposure to cold environment or emotional stress.
If idiopathic, it is called Raynaud's disease. If associated with a possible precipitating systemic or regional disorder (autoimmune diseases, myeloproliferative disorders, multiple myeloma, cryoglobulinemia, myxedema, macroglobulinemia, or arterial occlusive disease), it is called Raynaud’s phenomenon ... more » »
A new discovery published in the October 2011 print issue of The FASEB Journal explains for the first time what kicks off the process that causes varicose veins. In the article, researchers from Germany describe a single protein…
An international consortium of scientists reports the discovery of five new genes that affect the risk of developing coronary artery disease (CAD) and heart attacks in a study published in the open-access journal PLoS Genetics.
A new study published in the November 2011 issue of Stroke reveals some promising data on the positive effects of soy protein reducing the progression of clogged arteries in women who were within five years of menopause. This…
A new and better understanding of blood vessel growth and vascular development (angiogenesis) in cancer has been made possible by research carried out by a team of scientists from Moffitt Cancer Center, the University of Florida, Harvard University,…
HLS (High ligation and stripping) and EVLT (endovenous laser treatment) have similar efficacy and safety rates in the treatment of insufficiency of the great saphenous vein (GSV), but there are slightly more cases of recurrences after EVLT than…
Peripheral arterial disease, or PAD, is a common condition affecting 12-20 percent of Americans age 65 and older that may be a signal of future heart attack and stroke—and many with the disease may be unaware they have…
