Neoplasms of the Head and Neck
Head and neck cancer Adjuvant Chemotherapy
Adjuvant chemotherapy to eradicate micrometastases following local therapy has not been studied extensively in HNSCC. The principal…
Head and neck cancer Concomitant Chemoradiotherapy
Concomitant chemoradiotherapy is the most promising primary chemotherapy approach to prolonging the survival of patients with locally…
Primary Chemotherapy - Head and neck cancer
Although chemo-therapy has not improved the short-term survival of patients with recurrent or metastatic HNSCC, promising results…
Multiagent Trials - Head and neck cancer
Nearly all possible combinations and combination doses/schedules of methotrexate, cisplatin, bleomycin, and 5-FU and other agents listed…
Neoadjuvant Therapy - Head and neck cancer
Neoadjuvant (induction) therapy prior to surgery is sometimes referred to as sequential chemoradiotherapy when chemotherapy is followed…
Chemotherapy - Head and neck cancer
Overview
The role of chemotherapy in the primary treatment of locally advanced head and neck…
Chemotherapy of Recurrent HNSCC - Head and neck cancer
Clinical testing of new cytotoxic agents traditionally has been conducted first in patients with recurrent disease, followed…
Combined Surgery and Radiotherapy - treatment of head and neck cancer
Radiotherapy is often given as an adjuvant to surgery for moderately advanced but resectable tumors. For most head…
Curative Radiotherapy - Head and neck cancers Radiation Therapy
HNSCC responds to radiation injury through a loss of reproductive capability, resulting in a clonogenic rather than…
Concomitant Chemotherapy and Radiotherapy - treatment of head and neck cancer
There are two basic intents to the addition of chemotherapy to the treatment regimen for head and neck…
Accelerated and Hyperfractionated Radiotherapy - treatment of head and neck cancer
Accelerated and Hyperfractionated Radiotherapy - treatment of head and neck cancer
An area of current interest…
Head and neck cancers Radiation Therapy
Radiotherapy plays an integral role in the treatment of most head and neck cancers. Used as the sole…
Technologic Advances - Head and neck cancers Radiation Therapy
Advances in radiotherapy have been tied to advances in technology. In the early days, low-energy orthovoltage devices and…
Salivary Glands cancers
Anatomy
Salivary gland tissue is ubiquitous in the submucosa of the upper gastrointestinal tract and is…
Sarcomas of the Head and Neck
Overview
Overall, sarcomas are particularly rare neoplasms as they constitute only 1% of all cancer…
The Nasopharynx - nasopharyngeal carcinoma
In the United States, nasopharyngeal carcinoma (NPC) accounts for 2% of all…
Nose and Paranasal Sinuses cancers
As mentioned previously, the nose and the paranasal sinuses pose a unique set of problems that deserve separate…
Skin - cutaneous malignancies
Although the skin of the head and neck accounts for less than 10% of the body’s surface area,…
Carcinoma in Situ
A special issue relates to the treatment of carcinoma in situ of the vocal cords. This disease often…
Glottic and Subglottic Cancers treatment
The treatment of glottic cancer is greatly influenced by the secondary goal of voice preservation. Mobility of the…
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