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  You are here : Health.am > Health Centers > Cancer Health CenterVaginal Cancers

Cancer of the Vagina

Vaginal CancersNov 08, 2007

Primary vaginal cancers are rare, constituting less than 2% of all gynecologic malignancies. Carcinoma of the vagina is defined as a primary carcinoma arising in the vagina and not involving the external os of the cervix superiorly or the vulva inferiorly.

Vaginal cancer is rare and accounts for only about 3% of cancers of the female reproductive system. The American Cancer Society estimates that in 2005, about 2,140 new cases of vaginal cancer will be diagnosed in the United States and 810 women will die of this cancer.

The most common symptom of vaginal carcinoma is abnormal bleeding or discharge. With advanced tumors, pain or urinary frequency occasionally occurs, especially in cases of anterior wall tumors. Constipation or tenesmus has been seen with tumors involving the posterior vaginal wall. These tumors usually are diagnosed by direct biopsy of the tumor mass, and abnormal cytologic findings often will lead to diagnosis of a vaginal cancer.

The staging criteria for vaginal carcinomas according to the FIGO are given in Table 100-5.





Cancer of the Vagina



Woodruff JD, Genadry R, Poliakoff S. Treatment of dyspareunia and vaginal outlet distortions by perineoplasty. Obstet Gynecol 1981;57:750.
REFERENCES

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3. Sutton GP, Stehman FB, Ehrlich CE, Roman A. Human papilloma virus deoxyribonucleic acid in lesions of the female genital tract: evidence for types 6/11 in squamous carcinoma of the vulva. Obstet Gynecol 1987;70:564.

4. Crum CP. Vulvar intraepithelial neoplasia: histology and associated viral changes. In: Wilkinson EJ, editor. Pathology of the vulva and vagina. New York: Churchill Livingstone; 1987.

5. Planner RS, Hobbs JB. Intraepithelial and invasive neoplasia of the vulva in association with human papillomavirus infection. J Reprod Med 1988;33:503.

6. Basta A, Adamek K, Pitynski K. Intraepithelial neoplasia and early stage vulvar cancer: epidemiological, clinical and virological observations. Eur J Gynaecol Oncol 1999;20:111-4.

7. Mabuchi K, Bross DS, Kessler II. Epidemiology of cancer of the vulva: a case control study. Cancer 1985;55:1843-8.

8. Buscema J, Woodruff JD, Parmley TH, Genadry R. Carcinoma in situ of the vulva. Obstet Gynecol 1980;55:225.

9. Skinner MS, Sternberg WH, Inchinose H, et al. Spontaneous regression of bowenoid atypia of the vulva. Obstet Gynecol 1973;42:40.

10. Chafe W, Richards A, Morgan L, Wilkinson E. Unrecognized invasive carcinoma in vulvar epithelial neoplasia (VIN). Gynecol Oncol 1988;31:154.

11. Friedrich EG. Vulvar disease. 2nd ed. Philadelphia: W.B. Saunders; 1983.

12. Fredrich EF, Wilkinson EJ, Fu YS. Carcinoma in situ of the vulva: a continuing challenge. Am J Obstet Gynecol 1980;136:830.

13. International Society for the Study of Vulvar Disease new nomenclature for vulvar disease. Obstet Gynecol 1976;47:122.

14. Hart WR, Norris HJ, Helwig ED. Relation of lichen sclerosus et atrophicus of the vulva to development of carcinoma. Obstet Gynecol 1975;45:369.

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16. Fu YS, Reagan JW, Townsend DE, et al. Nuclear DNA study of vulvar intraepithelial and invasive squamous neoplasms. Obstet Gynecol 1981;57:643.

17. Rutledge F, Sinclair M. Treatment of intraepithelial neoplasia of the vulva by skin excision and graft. Obstet Gynecol 1968;102:806.

18. Woodruff JD, Genadry R, Poliakoff S. Treatment of dyspareunia and vaginal outlet distortions by perineoplasty. Obstet Gynecol 1981;57:750.

19. Leuchter RS, Hacker NF, Voet RL, et al. Primary carcinoma of the Bartholin gland: a report of 14 cases and review of the literature. Obstet Gynecol 1982;60:361.

20. Helwig EP, Graham JH. Anogenital (extramammary) Paget’s disease. Cancer 1963;16:387.

21. Lee SC, Roth LM, Ehrlich C, Hall JA. Extramammary Paget’s disease of the vulva—a clinicopathologic study of 13 cases. Cancer 1977;39:2540.

22. Friedrich EG Jr, Wilkinson EJ, Steingraeber PH, Lewis JD. Paget’s disease of the vulva and carcinoma of the breast. Obstet Gynecol 1975;46:130.

23. Bergen S, DiSaia PJ, Liao SY, Berman ML. Conservative management of extramammary Paget’s disease of the vulva. Gynecol Oncol 1989;33:151.

24. Creasman WT. New gynecologic cancer staging. Obstet Gynecol 1990;75:287.

25. Iversen T, Aas M. Lymph drainage from the vulva. Gynecol Oncol 1983;16:179.

Provided by ArmMed Media

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