High colon cancer risk with diabetes confirmed

	Tweet

Men and women with diabetes are at increased risk for developing cancer of the colon and rectum, according to a report from Sweden.

The findings are based on an analysis of data pooled from 15 studies, which included more than 2.5 million subjects. Most, but not all, studies have shown a link between diabetes and colon cancer, but some inconsistencies were present, including whether the association was seen in both men and women.

Dr. Susanna C. Larsson, from the Karolinska Institute in Stockholm, and colleagues found that diabetes increased the risk of colorectal cancer by 30 percent. The results were similar in US and European studies, the investigators report in the Journal of the National Cancer Institute.

Further analysis failed to uncover a significant difference between men and women. Likewise, diabetes raised the risk of colon and rectal cancers to a similar extent, by 43 percent and 33 percent, respectively.

“These findings provide evidence for a role of hyperinsulinemia or factors related to insulin resistance in colorectal carcinogenesis,” the researchers conclude.

“Our results,” they add, “have important clinical and public health implications,” especially in light of the increase in diabetes that is expected with the growing obesity epidemic in the US and elsewhere.

SOURCE: Journal of the National Cancer Institute, November 16, 2005.

RELATED STORIES:
Smoking can double risk of colorectal polyps   Study reveals differences in cancer stage presentation between rural and urban patients   Water method for unsedated colonoscopy; interval between prep and colonoscopy predicts prep quality   Following lifestyle tips could prevent almost a quarter of bowel cancer cases   Hour of daily exercise cuts bowel cancer risk   Women fare better than men with metastatic colorectal cancer—are hormones helping?   Hormone therapy associated with reduced colorectal cancer risk   Hydrophobic proteins: Potential biomarkers for colorectal cancer   Protein Levels Indicate Risk of Death in Some Colorectal Cancer Patients   Poor less likely to be screened for colon cancer   Cigarette smoking linked with rectal cancer risk   Study showed oxaliplatin improved colon cancer patient survival   Novel feces analysis may help detect colon cancer   Study confirms red meat link with bowel cancer   Genetic ID of Marker in Lymph Nodes May be Linked to Colorectal Cancer Recurrence Risk   Occult blood test reduces colorectal cancer crises   Obesity tied to poorer colon cancer survival   Confirmation that vitamin D acts as a protective agent against the advance of colon cancer   New report says racial gap growing in colorectal cancer   Consistent exercise associated with lower risk of colon cancer death   Diet high in meat, fat and refined grains linked to risk for colon cancer recurrence, death   Colorectal Cancer Screening Rates Still Too Low

Comments

[ + Post Your Own ]

Now you're in the public comment zone. What follows is not Armenian Medical Network's stuff; it comes from other people and we don't vouch for it. A reminder: By using this Web site you agree to accept our Terms of Service. Click here to read the Rules of Engagement.

There are no comments for this entry yet. [ + Comment here + ]