UCI study finds racial, economic disparities in ovarian cancer care, survival

Only 20 to 30 percent of ovarian cancers are diagnosed while still confined to the primary site; the remainder are identified in advanced stages after spreading to areas such as the liver, the lungs and nearby lymph nodes.

Bristow’s study was part of an effort by the Society of Gynecologic Oncology and colleagues at the Mayo Clinic and Washington University in St. Louis to assess the quality and outcomes of ovarian cancer care in the U.S.

Black Women, Uninsured Get Worse Ovarian Cancer Care: Study

Women with ovarian cancer who are black, either uninsured or Medicare recipients, or who have annual incomes of less than $35,000 are more likely to receive poorer-quality care, a new study shows.
Researchers found these racial and socioeconomic disparities in ovarian cancer care also are associated with worse odds of surviving for five years after their cancer diagnosis.

The study examined more than 47,000 women treated for ovarian cancer between 1998 and 2002. Fewer than half of the women (44 percent) received treatment that fit within guidelines developed by a group of the top cancer centers in the world and recommended by the National Comprehensive Cancer Network.

Black women, women who were uninsured or on Medicare and women of lower socioeconomic status were less likely than other women to receive the recommended treatment.

About UC Irvine Medical Center: Orange County’s only university hospital, UC Irvine Medical Center offers acute- and general-care services at its new, 482,000-square-foot UC Irvine Douglas Hospital and is home to the county’s only Level I trauma center, American College of Surgeons-verified regional burn center and National Cancer Institute-designated comprehensive cancer center. U.S. News & World Report has included UC Irvine for 11 consecutive years on its list of America’s Best Hospitals, giving special recognition to its urology, gynecology, kidney disorders and cancer programs.

Recurrent ovarian cancer

Once your treatment is complete and there is a remission (absence of cancer symptoms; also called “no evidence of disease” or NED), talk with your doctor about the possibility of the cancer returning. Many survivors feel worried or anxious that the cancer will come back. Learn more about coping with this fear.

If the cancer does return after the original treatment, it is called recurrent cancer. It may come back in the same place (called a local recurrence), nearby (regional recurrence), or in another place (distant recurrence).

When this occurs, a cycle of testing will begin again to learn as much as possible about the recurrence. After testing is done, you and your doctor will talk about your treatment options. Often the treatment plan will include the therapies described above (such as surgery, chemotherapy, and radiation therapy) but may be used in a different combination or given at a different pace. Your doctor may also suggest clinical trials that are studying new ways to treat this type of recurrent cancer.

The symptoms of recurrent ovarian cancer are similar to those experienced when the disease was first diagnosed. The four of the most common symptoms are bloating, pelvic or abdominal pain, difficulty eating or feeling full quickly, urinary symptoms (urgency or frequency). However, other symptoms may include persistent indigestion, gas, nausea, diarrhea, or constipation; unexplained weight loss or gain, especially in the abdominal area; abnormal bleeding from the vagina; pain during intercourse; fatigue; and lower back pain.

Doctors can also monitor ovarian cancer recurrence by measuring the level of CA-125 in the blood. CA-125 is a cancer antigen, or a substance that is found in higher levels on the surface of ovarian cancer cells.

People with recurrent cancer often experience emotions such as disbelief or fear. Patients are encouraged to talk with their health care team about these feelings and ask about support services to help them cope.

About the University of California, Irvine: Founded in 1965, UCI is a top-ranked university dedicated to research, scholarship and community service. Led by Chancellor Michael Drake since 2005, UCI is among the most dynamic campuses in the University of California system, with nearly 28,000 undergraduate and graduate students, 1,100 faculty and 9,000 staff. Orange County’s second-largest employer, UCI contributes an annual economic impact of $4 billion. For more UCI news, visit http://www.today.uci.edu.

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— Orange, Calif., May 08, 2012 —

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