Understanding of the mechanisms involved in the induction of immunity and the recognition of antigens by effector cells has improved dramatically in the past decade as molecular biology has joined forces with classic tumor immunology.…

TAAs can be useful tumor markers in the diagnosis and management of various tumors. An ideal tumor marker is released only from tumor tissue, is specific for a given tumor type (to direct diagnostic assessment),…

Interferons (IFNs) derived from WBCs (IFN-α- and IFN-γ) or from fibroblasts (IFN-β) or synthesized in bacteria by recombinant genetic techniques are glycoproteins that have antitumor and antiviral activity, which may originate partially from immunologically mediated…

Immunotherapy for cancer is best thought of as part of a broader subject, namely biologic therapy, or the application of biologic-response modifiers (BRMs). These agents can act through one or more mechanisms (1) to stimulate the…