The relative risk (RR) of incidence of haemorrhagic stroke was 2.72 times compared with that in the IUD users. Furthermore, the RR of current users of HC was 4.20 and still reached 2.17 among past users after they stopped taking HC for more than 10 years ⁽³³⁾.

While,other studies had found no statistically significant increase in the risk of stroke among HC past users without other risk factors.In fact,  for past users compared with never users the odds ratio was 0.59 ⁽³⁴⁾.

Current users of low-dose oral contraceptives had a risk for stroke similar to that of women who have never used these medications and the results did not differ appreciably between Hemorrhagic stroke and ischaemic stroke.

Although other studies reported that the incidence of total stroke among 18-44 –year-old was 11.3 per 100,000 women-years,  and the rate of haemorrhagic stroke was higher than the rate of ischemic stroke (6.4 per 100.000 women-year compared with 4.3 per 100.000 women-year). 

Compared   with   women   who   had   never   used   com   bined   oral contraceptives(COCs), current users of low-dose COCs had estimated odds tatio of 0.93 for hemorrhagic stroke and 0.89 for ischemic stroke ^(35,36,37).

There is insufficient information to determine whether major differences in the risk of ischaemic stroke exist between different formulations.

Data examining the risk of haemorrhagic stroke in current COC users with other risk factors are very sparse, as are those relating to the haemorrhagic stroke risk associated with particular COCs.  Literature   data   are   scarce   and   sometimes   showed   methodological limitations. There is a discrepancy between the different studies.

It is important to remember that we define stroke as the rapid onset of loss of cerebral function that lasted at least 24 hours and could not be ascribed to subdural hematoma or to other diseases:  neurologic, neoplastic, infection, seizure or multiple sclerosis.