The Prepubertal Girl
Diaper Dermatitis in Infancy
Rashes in the diaper area are common in babies between the ages of 7 and 12 months. Most…
Gonadotrophin-Independent Precocious Puberty
GIPP occurs more commonly in boys (described as testotoxicosis) than in girls. However, when it does occur in…
Ambiguous Genitalia in the Newborn: Diagnosis, Etiology and Sex Assignment
René Benoit Galifer, Jean-Charles Picaud
Diagnosis of Ambiguous Genitalia in the Newborn
Diagnosis of Ambiguous Genitalia in the Newborn
When a genital defect is discovered in the neonatal…
Etiology of Ambiguous Genitalia in the Newborn
Etiology of Ambiguous Genitalia in the Newborn
Generally, the medical team has a final diagnosis and…
Sex Assignment of the Intersex Child at Birth
When a child is born with ambiguous genitalia, the medical team must mobilize for a neonatal emergency: in…
Labial Adhesions
Labial Adhesions
Adherent or fused labia minora are a common problem in the pediatric population (rate:…
Tumoral and Hamartomatous Diseases of the Vulva
Vulvo-vaginal malignant tumors are uncommon in children but early diagnosis and prompt, effective treatment improves prognosis. Here, we…
Infectious Diseases (Except Sexually Transmitted Diseases)
Vulvo-Vaginitis
The prepubertal vulva is thin, delicate, and susceptible to trauma, infection and irritation as…
Lichen Sclerosus
Lichen Sclerosus
The true frequency of pediatric lichen sclerosus (LSV) is difficult to assess. The…
Vulvo-Perineal Localization of Dermatologic Disorders
Vulvo-Perineal Localization of Dermatologic Disorders
Systemic disorders may be localized in the vulvo-perineal region. Here,…
Adrenal Dysfunction
Various adrenal disorders may cause premature sexual maturation.
However, this does not involve ‘gonadarche’ and so…
Central Precocious Puberty
Central Precocious Puberty
This is known as central, idiopathic or gonadotrophin-dependent precocious puberty. The pattern of…
Isolated Premature Thelarche
Isolated Premature Thelarche
Premature thelarche is a benign, self-limiting condition which is characterised by breast development…
Thelarche Variant
Thelarche Variant
This encompasses a spectrum of conditions, which lie between premature thelarche and central precocious…
Isolated Menarche
Isolated Menarche
This is a condition where young girls have cyclical uterine bleeding without any other…
Vulvo-Vaginal Disorders
Service de Dermatologie, Hôpital Necker-Enfants Malades, Paris, France




