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Hyperandrogenism in Adolescent Girls

Treatment of Hyperandrogenism in Female Adolescents
• Hyperandrogenism in Adolescent Girls • Sep 21 06

PCOS
The treatment of hyperandrogenism in women with PCOS aims at interrupting androgen production and/or action. Suppression of ovarian function with oral contraceptives is usually the first line of therapy.…


 

Hyperandrogenism in Female Adolescents - Conclusions
• Hyperandrogenism in Adolescent Girls • Sep 21 06

In most cases, hyperandrogenism in adolescence is related to a nascent PCOS. Since the laboratory and ultrasonic findings are often not conclusive at this age, the diagnosis may remain presumptive providing…


 

Other Causes of Hyperandrogenism in Female Adolescents
• Hyperandrogenism in Adolescent Girls • • Causes • Sep 21 06

These causes of hyperandrogenism are rare. The clinical presentation is often suggestive (see above, Diagnosis of Hyperandrogenism in Female Adolescents). The laboratory investigations will rapidly confirm the clinical suspicion and…


 

Non-Classic Adrenal Hyperplasia
• Hyperandrogenism in Adolescent Girls • • Causes • Sep 21 06

NCAH is encountered with relatively high frequency (1 - 6%) among adolescent and adult patients with hyperandrogenism. This incidence may vary from one geographic area to another, as reported for classical 21-OHD, because of…


 

Classification of Polycystic Ovary Syndrome (PCOS)
• Hyperandrogenism in Adolescent Girls • • Causes • Sep 21 06

Actually, the difficulty of diagnosing PCOS varies according to the clinical presentation. In some cases, only one or two of the three above-mentioned components are present (e.g., ‘ovulatory PCOS’ or ‘non-hirsute…


 

Polycystic Ovary Syndrome Diagnosis
• Hyperandrogenism in Adolescent Girls • • Causes • Sep 21 06

Making the diagnosis of PCOS remains a difficult challenge and a controversial issue, especially in adolescent girls. In particular, whether ultrasonography should be used as a universal standard is still disputed.

Hormonal Markers…


 

Polycystic Ovary Syndrome Clinical Aspects
• Hyperandrogenism in Adolescent Girls • • Causes • Sep 21 06

Although very variable, the phenotypic features of PCOS can be schematically divided into three components, i.e., hyperandrogenic, anovulatory and dysmetabolic. These three components are not necessarily or fully associated.

Hyperandrogenism
Usually,…


 

The Physiological Hyperandrogenism of Puberty
• The Adolescent Girl • • Hyperandrogenism in Adolescent Girls • Sep 21 06

At the beginning of puberty, LH pulsatility is only present during sleep. It then extends to the daytime, with amplification of pulse amplitude and acceleration of frequency. This is accompanied by an…


 

Hyperandrogenism in Adolescent Girls
• The Adolescent Girl • • Hyperandrogenism in Adolescent Girls • Sep 21 06

Mild symptoms of hyperandrogenism, such as acne or hyperseborrhea, are frequent in adolescent girls, and are often associated with irregular menstrual cycles. In most instances, these symptoms are transient and only reflect the…


 

Causes of Hyperandrogenism in Female Adolescents
• The Adolescent Girl • • Hyperandrogenism in Adolescent Girls • • Causes • Sep 21 06

The Polycystic Ovary Syndrome
Pediatric and adult endocrinologists may encounter PCOS as a mildly virilizing state since it is the most frequent cause of hyperandrogenism in female teenagers and in…


 

Diagnosis of Hyperandrogenism in Female Adolescents
• The Adolescent Girl • • Hyperandrogenism in Adolescent Girls • Sep 21 06

Clinical Assessment
When an adolescent girl is referred for hyperandrogenism, the first visit must include a thorough record of history and a careful physical examination.

Although infrequent, some clinical symptoms…


 
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