Long-Term Use of Certain Contraception Injections Associated With Increased Fracture Risk

	Tweet

A new study presented May 6 at the World Congress on Osteoporosis (IOF WCO-ECCEO10) in Florence, Italy shows that DMPA, a commonly used injectible contraceptive, is associated with higher risk of bone fracture when used alone, and not in combination with estrogens.

Depot medroxyprogesterone acetate (DMPA) is a progestin-only long acting reversible hormonal contraceptive birth control drug which is injected every 3 months. It is used by more than 9 million women worldwide, with high usage among teenagers in Europe and the US.

Previous studies have shown that use of DMPA is associated with impaired bone acquisition during adolescence and accelerated bone loss later in life, mainly in younger women with lower estrogen levels. However, few studies have looked into the impact of DMPA on fracture risk.

The study, conducted by researchers at the University Hospital Basel, Switzerland and the Boston University Medical Center, Lexington, USA, used a case-control analysis to evaluate the relationship between long-term use of DMPA, with or without estrogen, and the risk of fractures. The results show that in women below 50 years of age, longer-term use of DMPA of two and more years is associated with a 50% increased risk of fracture. For users of combined estrogen-containing oral contraceptives fracture risk was not increased.

OC7—published in Osteoporosis International Vol. 21 Sup. 1

---
Story Source:  Adapted from materials provided by Osteoporosis Foundation">International Osteoporosis Foundation
International Osteoporosis Foundation (2010, May 6). Long-term use of certain contraception injections associated with increased fracture

RELATED STORIES:
Pill Among Least Effective Birth Control Methods   70 percent of women use contraceptives during their first sexual encounter   Long-term contraception more effective than pills   Gay couples and women over 40 to get free IVF treatment on NHS   Health secretary urges contraception compromise   Contraceptive ring, patch carry blood clot risks   Reminder Stamp Boosts HPV Vaccination   Study adds to evidence on clot risks of non-oral contraceptives   HPV vaccine completion rate among girls is poor, getting worse   Some ob-gyns cite religious conflicts over care   After IVF, some couples get pregnant without help   Web Tool Offers Map to Menopause   Early Menopause Could Also Mean Early Death   Does soy help cool hot flashes after all?   Caffeine not tied to worsening urinary incontinence

Comments

[ + Post Your Own ]

Now you're in the public comment zone. What follows is not Armenian Medical Network's stuff; it comes from other people and we don't vouch for it. A reminder: By using this Web site you agree to accept our Terms of Service. Click here to read the Rules of Engagement.

There are no comments for this entry yet. [ + Comment here + ]