Promethazine overdose

Alternative names 

Poisoning from an overdose of Phenergan.

Poisonous Ingredient

Where Found

  • Phenergan  
  • Promethegan  
  • Anergan  
  • Fargan  
  • Promahist  
  • V-Gan

Note: This list may not be all inclusive.


  • Body as a whole       o Unsteadiness       o Tremor       o Convulsions       o Fever       o Flushed skin       o Muscle stiffness in face and/or neck  
  • Heart and blood vessels       o Rapid heartbeat  
  • Nervous system       o Depression       o Excitation       o Drowsiness       o Nervousness       o Hallucinations       o Disorientation       o Delirium       o Coma

Home Treatment

Contact Poison Control for instructions.

Before Calling Emergency
Determine the following information:

  • The patient’s age, weight, and condition  
  • Name of product (as well as the ingredients and strength if known)  
  • The time it was swallowed  
  • The amount swallowed  
  • If the medication was prescribed for the patient

Poison Control, or a local emergency number
They will instruct you if it is necessary to take the patient to the hospital. See Poison Control centers for telephone numbers and addresses. Take the container with you to the emergency room.

What to expect at the emergency room
Some or all of the following procedures may be performed:

  • Administer activated charcoal.  
  • Administer a laxative.  
  • Use gastric lavage.  
  • Treat the symptoms.

Expectations (prognosis)
If the patient survives the first 24 hours, recovery is likely. Few patients actually die from an antihistamine overdose.

Johns Hopkins patient information

Last revised: December 8, 2012
by Brenda A. Kuper, M.D.

Medical Encyclopedia

  A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | 0-9

All ArmMed Media material is provided for information only and is neither advice nor a substitute for proper medical care. Consult a qualified healthcare professional who understands your particular history for individual concerns.