Percodan overdose

Poisoning from an overdose of Percodan.

Poisonous Ingredient 

  • Oxycodone  
  • Aspirin

Where Found 

  • Percodan  
  • Roxiprin  
  • Percodan-Demi

Note: This list may not be all inclusive.


  • Respiratory       o Breathing difficulty (shallow, slow, or labored)       o No breathing  
  • Eyes, ears, nose, and throat       o Pinpoint pupils  
  • Skin       o Cyanosis (bluish colored fingernails or lips)  
  • Gastrointestinal       o Abdominal cramps  
  • Heart and blood vessels       o Pulse, weak       o Low Blood pressure  
  • Nervous system       o Coma

Home Treatment 

Before Calling Emergency 
Determine the following information:

  • The patient’s age, weight, and condition  
  • Name of product (as well as the ingredients and strength if known)  
  • The time it was swallowed  
  • The amount swallowed  
  • If the medication was prescribed for the patient

Poison Control, or a local emergency number 
They will instruct you if it is necessary to take the patient to the hospital. See Poison Control centers for telephone numbers and addresses. Take the container with you to the emergency room.

What to expect at the emergency room 
Some or all of the following procedures may be performed:

  • Use gastric lavage.  
  • Administer activated charcoal.  
  • Administer a laxative.  
  • Give a counter-acting medication (narcotic antagonist). Multiple doses may be needed.  
  • Administer intravenous fluids as needed.  
  • Monitor breathing.  
  • Treat the symptoms

Expectations (prognosis) 
If an antidote can be given, recovery from an acute overdose occurs within 1 to 2 days.

Johns Hopkins patient information

Last revised: December 8, 2012
by Armen E. Martirosyan, M.D.

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All ArmMed Media material is provided for information only and is neither advice nor a substitute for proper medical care. Consult a qualified healthcare professional who understands your particular history for individual concerns.