Macroamylasemia is a condition in which macroamylase builds up in the blood.

Amylase is an enzyme that is filtered out of the blood by the kidneys. Macroamylase is a larger molecule consisting of amylase bound to a protein (an autoantibody). Unlike amylase, macroamylase is filtered very slowly from the blood by the kidneys. Having macroamylasemia causes an elevated amylase blood level reading.

Macroamylasemia has been associated with:

Approximately 1 percent of the population has macroamylasemia.

Johns Hopkins patient information

Last revised: December 7, 2012
by Sharon M. Smith, M.D.

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