A gumma is a soft, tumor-like growth of the tissues (granuloma) caused by syphilis. It appears during late stage, tertiary syphilis. It usually contains a mass of dead and swollen fiber-like tissue, and occurs most frequently in the liver but may also occur in the brain, testis, heart, skin, and bone. Also, similar-appearing granulomatous sores are sometimes found with tuberculosis.
by Janet G. Derge, M.D.
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