Doxepin overdose

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Alternative names
Adapin; Novoxapin; Sinequan; Triadapin

Definition
This is poisoning from an overdose of Doxepin.

Poisonous Ingredient
Doxepin

Where Found

• Sinequan
  
• Adapin
  
• Co-Dax
  
• Novoxapin
  
• Triadapin

This list may not be all inclusive.

Symptoms

• Body as a whole
  o Dry mouth
  o Urinary hesitancy
  o Muscle rigidity
  o Convulsions
  o Shock
  o Incoordination
  
• Respiratory
  o Breathing slowed and labored
  
• Eyes, ears, nose, and throat
  o Blurred vision
  o Photosensitivity
  o Ringing in the ears
  
• Gastrointestinal
  o Vomiting
  o Nausea
  o Constipation
  o Unpleasant taste
  
• Heart and blood vessels
  o Irregular heartbeat
  o Low blood pressure
  
• Nervous system
  o Drowsiness
  o Headache
  o Confusion
  o Stupor
  o Coma
  o Agitation
  o Restlessness

Home Treatment
Call Poison Control.

Before Calling Emergency
Determine the following information:

• the patient’s age, weight, and condition
  
• the name of the product (ingredients and strengths if known)
  
• the time it was swallowed
  
• the amount swallowed
  
• if the medication was prescribed for the patient

Poison Control, or a local emergency number
They will instruct you if it is necessary to take the patient to the hospital. See Poison Control centers for telephone numbers and addresses. Take the container with you to the emergency room.

What to expect at the emergency room
Some or all of the following procedures may be performed:

• Use activated charcoal.
  
• Use gastric lavage.
  
• Monitor vital signs (temperature, pulse, rate of breathing, blood pressure).
  
• Maintain the airway.
  
• Replace fluids if appropriate.
  
• Treat the symptoms.

Expectations (prognosis)
The amount swallowed and the time before appropriate therapy is initiated usually determine the final outcome. Patients have died as late as 72 hours after an overdose ingestion. The sooner therapy is applied, the greater the chance of a positive outcome.

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