Ketorolac Tromethamine (Oral)

Ketorolac Tromethamine (By Mouth)

Ketorolac Tromethamine (kee-toe-ROLE-ak troe-METH-a-meen)

Treats pain.Belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs).

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to ketorolac, aspirin, or any pain and arthritis medicines such as Motrinreg;, Naprosynreg; or Alevereg;, Clinorilreg;, or Indocinreg;. The reaction may have included wheezing or trouble breathing, hives, rash, or swelling in the face.

How to Use This Medicine:


  • Your doctor will tell you how much to take and how often.  
  • Take your tablets with a full glass of water.  
  • You may take the medicine with food, milk, or antacids (such as Maaloxreg; or Mylantareg;) so it does not upset your stomach.

If a dose is missed:

  • Take the missed dose as soon as possible.  
  • Skip the missed dose if it is almost time for your next regular dose.  
  • You should not use two doses at the same time.

How to Store and Dispose of This Medicine:

  • Store at room temperature, away from heat, moisture, and direct light.  
  • Keep all medicine out of the reach of children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • You should not use this medicine with aspirin or products that contain aspirin, naproxen (Alevereg;), or ibuprofen (Advilreg; or Motrinreg;).  
  • Avoid drinking alcohol while you are taking this medicine.

Warnings While Using This Medicine:

  • Talk with your doctor before taking this medicine if you are pregnant, breastfeeding, or have heart disease, high blood pressure, liver or kidney disease, blood disorders, or ulcers or other stomach problems.  
  • You should not use this medicine for more than 5 days unless your doctor has told you to.  
  • Ulcers and stomach bleeding are sometimes caused by this type of medicine. These problems can happen without warning signs. You may need to see your doctor for regular check-ups while being treated with this medicine.  
  • Ketorolac may cause drowsiness and dizziness. Be careful if you are driving a car or using dangerous machinery.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Severe rash or hives  
  • Rapid swelling of face or around eyes  
  • Chest tightness or trouble breathing  
  • Sore throat or fever  
  • Unusual bleeding or bruising  
  • Yellowing of skin or eyes  
  • Decreased amount of urine  
  • Severe stomach pain or vomiting blood  
  • Bloody or black, tarry stools

If you notice these less serious side effects, talk with your doctor:

  • Mild stomach pain  
  • Nausea  
  • Diarrhea  
  • Drowsiness or dizziness  
  • Headache  
  • Swelling of feet or legs or weight gain

Johns Hopkins patient information

Copyright 1996-2014 Cerner Multum, Inc. Version: 16.02.
Revision date: July 4, 2011
Last revised: by Jorge P. Ribeiro, MD

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

The drug reference included in this section is provided by Cerner Multum, Inc., of Denver, Colorado. Armenian Medical Network receives monthly updates from Multum.