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Hypoglycemia in Type 2 Diabetes

Risk Factors for Hypoglycemia
• Hypoglycemia in Type 2 Diabetes • Sep 10 08

The conventional risk factors for iatrogenic hypoglycemia (5,6,22) are based on the premise that absolute or relative insulin excess is the sole determinant of risk (Table 4). Absolute or…


 

Risk Factor Reduction
• Hypoglycemia in Type 2 Diabetes • Sep 10 08

The prevention of iatrogenic hypoglycemia is similar in advanced type 2 diabetes and type 1 diabetes (6,22). Hypoglycemia risk reduction involves:

  • Addressing the issue of hypoglycemia in every patient contact.
    • …

 

Pathophysiology of Glucose Counter-Regulation
• Hypoglycemia in Type 2 Diabetes • Sep 10 08

PATHOPHYSIOLOGY OF GLUCOSE COUNTER-REGULATION
While marked hyperinsulinemia alone can cause hypoglycemia, iatrogenic hypoglycemia is the result of the interplay of relative or absolute insulin excess and compromised physiological and behavioral defenses against…


 

Clinical Diagnosis of Hypoglycemia
• Hypoglycemia in Type 2 Diabetes • Sep 10 08

It is not possible to specify a plasma glucose concentration that defines clinical hypoglycemia in people with diabetes because the glycemic thresholds for the manifestations of hypoglycemia shift to higher than normal glucose…


 

Frequency of Hypoglycemia
• Hypoglycemia in Type 2 Diabetes • Sep 10 08

Hypoglycemia is a fact of life for most people with established (i.e., C-peptide negative) type 1 diabetes (5,6). Those attempting to achieve some degree of glycemic control suffer untold numbers of episodes…


 

Hypoglycemia in Type 2 Diabetes
• Hypoglycemia in Type 2 Diabetes • Sep 10 08

Hypoglycemia: The Limiting Factor
Comprehensive treatment, including glycemic control, makes a difference for people with diabetes. Glycemic control prevents or delays the microvascular complications - retinopathy, nephropathy and neuropathy - of…


 
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