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Essentials of Diagnosis

• Precordial chest pain, usually precipitated by stress or exertion, relieved rapidly by rest or nitrates.
• Electrocardiographic or scintigraphic evidence of ischemia during pain or stress testing.…

Patients with long-standing alcoholism who undergo heart surgery are four times more likely to acquire an infection after the operation than their non-alcoholic peers, according to a new report.…

Embryonic stem cell research moved a step forward on Friday as French scientists reported they had used master cells from mice to repair heart damage in sheep.

Researchers at…

Coronary heart disease, or atherosclerotic coronary artery disease, is the commonest cause of cardiovascular disability and death in the United States. Men are more often affected than women by an…

Although many risk factors for coronary artery disease are not modifiable, it is now clear that interventions such as smoking cessation, treatment of dyslipidemia, and lowering of blood pressure…

Advanced coronary atherosclerosis and even complete occlusion may remain clinically silent. There is only a modest correlation between the clinical symptoms and the anatomic extent of disease. At present,…

Essentials of Diagnosis

Tricuspid regurgitation may occur in a variety of situations other than disease of the tricuspid valve itself. The most common is right ventricular overload resulting from left ventricular failure due to any cause. Tricuspid regurgitation…

Essentials of Diagnosis

• Variable causes determine clinical presentation.
• May be asymptomatic for many years (or for life) or may cause left-sided heart failure.
• Pansystolic murmur at the apex,…

Valve repair may be useful for tricuspid, mitral, and occasionally aortic regurgitation. Likewise, percutaneous or open valvulotomy may be indicated in mitral, pulmonary, and tricuspid stenosis. Nonetheless, the number of valve…

Tricuspid stenosis is usually rheumatic in origin. It should be suspected when “right heart failure” appears in the course of mitral valve disease, marked by hepatomegaly, ascites, and dependent edema. It may also occur in…

Essentials of Diagnosis

• Usually asymptomatic until middle age; presents with left-sided failure or chest pain.
• Wide pulse pressure with associated peripheral signs.
• Hyperactive, enlarged left ventricle.
• Diastolic murmur along left…

Essentials of Diagnosis

• In adults, usually asymptomatic until middle or old age.
• Delayed and diminished carotid pulses.
• Soft, absent, or paradoxically split S₂.
• Harsh systolic murmur, sometimes with thrill…

While most cases of valvular disease in the United States were at one time due to rheumatic heart disease (still true in developing countries), other causes are now more common. The typical findings of…

Essentials of Diagnosis

• Usually asymptomatic until middle age.
• Right ventricular lift; S₂ widely split and fixed.
• Grade I-III/VI systolic ejection murmur at pulmonary area.
• ECG…

Essentials of Diagnosis

• Adults asymptomatic if defect is small to moderate.
• Grade II-VI/VI pansystolic murmur maximal at the left sternal border; associated thrill common.
• ECG may show left ventricular hypertrophy…

Essentials of Diagnosis

• Adults with small or moderately large patent ductus are usually asymptomatic at least until middle age.
• Widened pulse pressure; loud S₂.
• Continuous murmur over pulmonary area; thrill…

Essentials of Diagnosis

• No symptoms in patients with mild or moderately severe lesions.
• Severe cases may present with right-sided heart failure and cause sudden death.
• High-pitched systolic ejection murmur maximal in…