Red wine: Exercise in a bottle?

	Tweet

As strange as it sounds, a new research study published in the FASEB Journal (http://www.fasebj.org), suggests that the “healthy” ingredient in red wine, resveratrol, may prevent the negative effects that spaceflight and sedentary lifestyles have on people. The report describes experiments in rats that simulated the weightlessness of spaceflight, during which the group fed resveratrol did not develop insulin resistance or a loss of bone mineral density, as did those who were not fed resveratrol.

According to Gerald Weissmann, M.D., Editor-in-Chief of the FASEB Journal, “There are overwhelming data showing that the human body needs physical activity, but for some of us, getting that activity isn’t easy. A low gravity environment makes it nearly impossible for astronauts. For the earthbound, barriers to physical activity are equally challenging, whether they be disease, injury, or a desk job. Resveratrol may not be a substitute for exercise, but it could slow deterioration until someone can get moving again.”

Scientists studied rats that underwent simulated weightlessness by hindlimb tail suspension and were given a daily oral load of resveratrol. The control group showed a decrease in soleus muscle mass and strength, the development of insulin resistance, and a loss of bone mineral density and resistance to breakage. The group receiving resveratrol showed none of these complications. Study results further demonstrated some of the underlying mechanisms by which resveratrol acts to prevent the wasting adaptations to disuse-induced mechanical unloading. This study also suggests that resveratrol may be able to prevent the deleterious consequences of sedentary behaviors in humans.

"If resveratrol supplements are not your cup of tea,” Weissmann added, “then there’s good news. You can find it naturally in red wine, making it the toast of the Milky Way.”

###

Receive monthly highlights from the FASEB Journal by e-mail. Sign up at http://www.faseb.org/fjupdate.aspx. The FASEB Journal (http://www.fasebj.org) is published by the Federation of the American Societies for Experimental Biology (FASEB) and celebrates its 25th anniversary in 2011. Over the past quarter century, the journal has been recognized by the Special Libraries Association as one of the top 100 most influential biomedical journals of the past century and is the most cited biology journal worldwide according to the Institute for Scientific Information.

FASEB comprises 24 societies with more than 100,000 members, making it the largest coalition of biomedical research associations in the United States. FASEB enhances the ability of scientists and engineers to improve - through their research - the health, well-being and productivity of all people. FASEB’s mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.

Details: Iman Momken, Laurence Stevens, Audrey Bergouignan, Dominique Desplanches, Floriane Rudwill, Isabelle Chery, Alexandre Zahariev, Sandrine Zahn, T. Peter Stein, Jean Louis Sebedio, Estelle Pujos-Guillot, Maurice Falempin, Chantal Simon, Véronique Coxam, Tany Andrianjafiniony, Guillemette Gauquelin-Koch, Florence Picquet, and Stéphane Blanc. Resveratrol prevents the wasting disorders of mechanical unloading by acting as a physical exercise mimetic in the rat.

###

Contact: Cody Mooneyhan

301-634-7104
Federation of American Societies for Experimental Biology

RELATED STORIES:
Tomato juice could reduce heart disease risk   Conflicting Food Messages May Put Consumers At Risk   Gene codes cracked for strawberries and chocolate   Eating more fish may improve seniors’ memory   Fish oil supplements lower lupus symptoms   Study suggests junk food in schools doesn’t cause weight gain among children   Antifibrotic effects of green tea   Milk and Dairy Products Protect Against “Metabolic Syndrome”   Cholesterol pills and grapefruit don’t mix   Research reveals link between beer and bone health   Americans eat too much salt, CDC says   Eating orange and dark green vegetables linked to longer life

Comments

[ + Post Your Own ]

Now you're in the public comment zone. What follows is not Armenian Medical Network's stuff; it comes from other people and we don't vouch for it. A reminder: By using this Web site you agree to accept our Terms of Service. Click here to read the Rules of Engagement.

There are no comments for this entry yet. [ + Comment here + ]