Cocaine Addiction

Substance Abuse in prisoners

The United States now incarcerates people at a rate nearly five times the world average primarily because of drug offenses. More than two-thirds of…    

Genetic Trait Could Triple Odds of Whites’ Susceptibility to Heavy Cocaine Abuse

Nearly one in five whites could carry a genetic variant that substantially increases their odds of being susceptible to severe cocaine abuse, according to…    

Anti-nausea drug may combat opiate addiction

Treatment with the drug ondansetron may lessen the symptoms of withdrawal in people addicted to morphine, oxycodone, and other opiate drugs, according to new…    

Drug-related preference in cocaine addiction extends to images

When given a choice between viewing pictures of cocaine and a variety of other images, cocaine addicted individuals, as compared to healthy, non-addicted research…    

Cocaine addicts’ brains predisposed to abuse

Cocaine addicts may have brain deficits that predispose them to drug abuse, and abusing drugs appears to make matters worse, U.S. researchers said on…    

Study finds abnormalities in cerebral cortex of cocaine addicts

A brain imaging study carried out at Massachusetts General Hospital (MGH) reveals abnormalities in the cortex – the outer surface of the brain –…    

Study examines use of opioids

Researchers from Boston University’s Slone Epidemiology Center have found that in a given week, over 10 million Americans are taking opioids, and more than…    

Research reveals molecular fingerprint of cocaine addiction

The first large-scale analysis of proteins in the brains of monkeys addicted to cocaine reveals new information on how long-term cocaine use changes the…    

Research sheds new light on heroin addiction

Researchers from the Howard Florey Institute in Melbourne have identified a factor that may contribute towards the development of heroin addiction by manipulating the…    

Marijuana use on the rise among Ontario adults, CAMH reports

Despite positive substance use trends, tobacco and alcohol still have high costs to society

While this CAMH Monitor eReport reveals some promising…    

Your Baby’s Brain on Drugs (And Alcohol and Tobacco)

Although behavioral studies clearly indicate that exposure to drugs, alcohol and tobacco in utero is bad for a baby’s developing brain, specific anatomic brain…    

Research Suggests Long-term Effects of Fetal Cocaine Exposure

Are the estimated 1 million young adults who were exposed to cocaine before birth more vulnerable to drug abuse today? New research indicating long-lasting…    

Environmental enrichment can reduce cocaine use, researchers find

Simple environmental enrichment and increased social stress can both affect the level of individual drug use, according to new monkey research at Wake Forest…    

Animal research suggests new strategy for treating cocaine addiction

New research in monkeys suggests the feasibility of treating cocaine addiction with a “replacement” drug that mimics the effects of cocaine but has less…    

Curing addiction with cannabis medicines

Smokers trying to quit in the future could do it with the help of cannabis based medicines, according to research from The University of…    

Withdrawal from Opioids

Opioid-withdrawal syndrome resembles a severe case of influenza. In addition, the symptoms include pupillary dilatation, lacrimation, rhinorrhea, piloerection ("gooseflesh"), yawning, sneezing, anorexia, nausea, vomiting,…    

Management of Drug and Alcohol Withdrawal

Each year in the United States, approximately 8.2 million persons are dependent on alcohol and 3.5 million are dependent on illicit drugs, including stimulants…    

The Cocaine-Abused Heart: Question and Answers

A 34-year-old African American man came to the emergency department (ED) complaining of chest pressure and shortness of breath, 2 hours in duration. He…    

Cocaine-Induced Dysrhythmias

The cardiac dysrhythmias that may occur with cocaine use are listed in Table 3, but the precise arrhythmogenic potential of the drug is poorly…    

Cocaine-Induced Myocardial Dysfunction

Long-term cocaine abuse has been reported to cause left ventricular hypertrophy and systolic dysfunction. Several reports have described dilated cardiomyopathy in long-term cocaine abusers,…    

Cocaine, Cigarette Smoking, and Alcohol Use

Many patients with cocaine-associated angina pectoris or myocardial infarction are cigarette smokers who admit to smoking while using cocaine. Cigarette smoking induces vasoconstriction of…    

Cocaine-Related Myocardial Ischemia and Infarction

In 1982, Coleman et al. reported an association between cocaine use and myocardial ischemia and infarction. Subsequently, many reports have documented cocaine-related myocardial ischemic…    

Cardiovascular Complications of Cocaine Use

The deaths of several celebrities in recent years in association with the nontherapeutic use of cocaine have focused widespread attention on the problem of…    

Pharmacotherapy for Cocaine Abuse and Dependence

Cocaine abuse and dependence may be initiated and perpetuated by a wide range of physiologic, behavioral, and sociocultural factors. Recent treatment-center evaluations of urban,…    

Pharmacologic Effects and Mechanisms of Abuse and Dependence

Cocaine is a stimulant as well as a local anesthetic with potent vasoconstrictor properties. It induces a complex pattern of subjective effects that have…