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A comparison of two types of medications to treat type 2 diabetes finds that pioglitazone is more effective at lowering the rate of progression of plaque build-up…

For a rich source of stem cells to be engineered into new blood vessels or skin tissue, clinicians may one day look no further than the…

New Deep Vein Thrombosis (DVT) Registry Data Show Clot Quickly Removed, Blood Flow Restored in Large Patient Registry

Registry data for more than 500 patients presented…

A commonly used medication that prevents blood clots from forming may also prevent existing clots from damaging delicate vein walls — and may accelerate healing in a clot-damaged area of…

They kill 300,000 people a year — but most of them could be prevented. They strike more than a million people every year, most of them out of…

University of Iowa researchers have identified a molecular pathway in blood vessels that controls blood pressure and vascular function and may help explain why certain drugs for type II…

About one in four patients in a population-based study who were treated for blood clots in major blood vessels died within 1 year after their initial diagnosis, a mortality rate…

Only 28 percent of American women are aware of peripheral arterial disease (P.A.D.), a common and dangerous vascular disease that affects approximately nine…

Genetic mutations in the enzyme methylenetetrahydrofoloate reductase (MTHFR) and coagulation protein Factor V appear to have significant association with blood clots and tissue injury to the placenta and developing…

A novel treatment for blood clots in the legs appears to be safe and effective, according to a pilot study published in the February issue of Radiology. The study found…

A procedure called carotid artery stenting (CAS) has emerged as a minimally invasive alternative to surgery, called carotid endarterectomy (CEA), for patients with dangerous narrowing of the arteries…

Strawberries are not only delicious and nutrient-rich, new research from Harvard Medical School found that they may offer cardiovascular disease protection. The new study found…

After an injury, the body grows new blood vessels to repair damaged tissue. But sometimes too much growth causes problems, as when new blood vessels in the…

Lower-limb complications
A minority of patients with intermittent claudication suffer from worsening leg symptoms (rest pain, ischaemic ulceration or gangrene). Estimates of the proportion of patients with intermittent claudication needing intervention, such…

The prevalence of diabetes in intermittent claudication is up to 20%, with some cases of diabetes previously undiagnosed (therefore, consider screening for diabetes).

Intermittent claudication is about twice as common in patients…

Questions that need to be answered before the ankle–brachial pressure index (ABPI) can be recommended for population screening

Answer is yes or probably yes:

1. Is ABPI a…

We prospectively evaluated the relationship between dietary fiber and peripheral arterial disease risk (PAD) among 46,032 men, aged 40 to 75 y, in 1986. Subjects answered a…

Since the practising of evidence-based medicine is deemed increasingly important, there is concern that current knowledge on the prevention of cardiovascular events may only benefit a minority of PAD patients. This notion is…

Individuals with peripheral arterial disease (PAD) have a significantly elevated risk of developing major cardiovascular complications, but, until recently, the atherosclerotic manifestation of PAD has…

Peripheral arterial disease is a prevalent manifestation of atherosclerosis that is associated with significant risk of morbidity and mortality and also a marked reduction in ambulatory capacity and quality of life. Unfortunately, PAD…

The initial management of patients with critical leg ischemia involves pain relief including narcotics. Patients with more severe disease including ischemic ulceration or gangrene also need wound care to control…

Claudication
In patients with claudication, the natural history of the limb disease is relatively benign in that the risk of progression to critical limb ischemia and limb loss is quite small. Therefore,…

The primary initial goals of medical therapy in patients with PAD are to treat the systemic atherosclerosis by risk modification and antiplatelet drugs in an attempt to reduce cardiovascular morbidity and mortality.…

In addition to risk factor modification, other therapies have been targeted to slow the progression of peripheral atherosclerosis, as well as to decrease the risk of cardiovascular morbidity and mortality. The…