Peripheral Arterial Disease

Peripheral arterial disease Prognosis

Lower-limb complications
A minority of patients with intermittent claudication suffer from worsening leg symptoms (rest pain, ischaemic ulceration or gangrene). Estimates of the…    

Diabetes and peripheral arterial disease

The prevalence of diabetes in intermittent claudication is up to 20%, with some cases of diabetes previously undiagnosed (therefore, consider screening for diabetes).

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Questions that need to be answered: peripheral arterial disease

Questions that need to be answered before the ankle–brachial pressure index (ABPI) can be recommended for population screening

Answer is yes or probably…    

Dietary Fiber Reduces Peripheral Arterial Disease Risk in Men: study

We prospectively evaluated the relationship between dietary fiber and peripheral arterial disease risk (PAD) among 46,032 men, aged 40 to 75 y, in 1986. Subjects…    

The management of PAD

Since the practising of evidence-based medicine is deemed increasingly important, there is concern that current knowledge on the prevention of cardiovascular events may only benefit…    

What does the future hold for the patient with peripheral arterial disease?

Individuals with peripheral arterial disease (PAD) have a significantly elevated risk of developing major cardiovascular complications, but, until recently, the atherosclerotic manifestation of PAD has…    

Critical Leg Ischemia in Peripheral Arterial Disease

The initial management of patients with critical leg ischemia involves pain relief including narcotics. Patients with more severe disease including ischemic ulceration or gangrene also…    

Peripheral Arterial Disease: Conclusions

Peripheral arterial disease is a prevalent manifestation of atherosclerosis that is associated with significant risk of morbidity and mortality and also a marked reduction in…    

Interventional Therapy for PAD

Claudication
In patients with claudication, the natural history of the limb disease is relatively benign in that the risk of progression to critical…    

Claudication Medical Therapy for Peripheral Arterial Disease

Exercise Training
The use of a formal exercise program to treat claudication has been studied over the past 30 years. Exercise therapy…    

Peripheral Arterial Disease Medical Therapy

The primary initial goals of medical therapy in patients with PAD are to treat the systemic atherosclerosis by risk modification and antiplatelet drugs in an…    

Antiplatelet Therapy for Peripheral Arterial Disease

In addition to risk factor modification, other therapies have been targeted to slow the progression of peripheral atherosclerosis, as well as to decrease the risk…    

Peripheral Arterial Disease Pathogenesis

The underlying disease process in PAD is the result of atherosclerosis in the arterial circulation of the lower extremity, caused by similar pathogenic mechanisms as…    

Risk Factors for Peripheral arterial disease (PAD)

The risk factors for PAD are those that are expected for any patient population with atherosclerosis. The most potent risk factors for PAD are age,…    

Peripheral Arterial Disease Clinical Presentation and Diagnosis

Clinical Assessment
PAD is associated with two very characteristic types of limb symptoms, intermittent claudication and ischemic rest pain. Claudication is derived…    

Peripheral arterial disease prevalence

Peripheral arterial disease affects eight million Americans and is associated with significant morbidity and mortality.  ₁

A study from the NHANES…