ZILEUTON - ORAL (zigh-LEW-ten)


This medication is used for the prevention and treatment of chronic asthma. It is not intended for acute attacks.

This drug may also be used to minimize breathing problems caused by exercising or sensitivity to aspirin.

Take as directed. Do not exceed the prescribed dosage. Treatment can be continued, even during acute asthma attacks. Do not stop taking this medication unless directed to do so by your doctor. Do not decrease the dose or stop taking any other anti-asthma medication unless directed by your physician.

Nausea, drowsiness, constipation and dizziness may occur. If these continue or are bothersome, notify your doctor. Notify your doctor if stomach pain or unusual weakness occur. Unlikely, but report yellowing of the skin or eyes, unusual fatigue or muscle aches, chest pain or insomnia. Notify your doctor immediately in the unlikely event an allergic reaction occurs. Symptoms include difficulty breathing, skin rash, itching or fever. If you notice other effects not listed above, contact your doctor or pharmacist.

Before taking this drug, tell your doctor if you have liver disease or any allergies. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into human milk. The manufacturer recommends you avoid breast-feeding while taking this drug. Consult your doctor. Asthmatic patients should always seek prompt medical attention if short-acting inhalers (bronchodilators) are needed more often than usual to treat wheezing or difficulty breathing. Limit alcohol intake due to the potential liver problems it can cause.

Tell your doctor of all nonprescription and prescription medication you may take, especially theophylline, warfarin, propranolol, terfenadine and astemizole. Do not start or stop any medicine without doctor or pharmacist approval.

If overdose is suspected, contact your local poison control center or emergency room immediately.

Do not share this medication with anyone.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not “double-up” the dose to catch up.

Store at room temperature between 68 and 77 degrees F (20-25 degrees C) away from light and moisture.

Your condition can cause complications in a medical emergency. For information on enrollment call Medic Alert(TM) at 1-800-854-1166. In Canada call 1-800-668-1507.

Johns Hopkins patient information

Copyright 1996-2014 Cerner Multum, Inc. Version: 16.02.
Revision date: June 20, 2011
Last revised: by Dave R. Roger, M.D.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

The drug reference included in this section is provided by Cerner Multum, Inc., of Denver, Colorado. Armenian Medical Network receives monthly updates from Multum.