Aquatensen, Diuril, Enduron, Esidrix, Hygroton, Naturetin, Oretic, Renese, Zaroxolyn

This medication is a “water pill” (diuretic) that decreases the amount of water in the body by increasing urination. It is used to decrease body fluid and swelling of the hands or feet (edema), and for high blood pressure.

Because this drug increases urination, it is best taken early in the day. This drug may be taken by mouth with food or milk to reduce stomach upset.

This drug may cause dizziness and lightheadedness especially during the first few days as your body adjusts to it. Rise slowly from a seated or lying position to minimize the dizziness or lightheadedness. Blurred vision, loss of appetite, itching, stomach upset, headache and weakness may also occur during initial therapy as your body adjusts to the medication. If these effects persist or worsen, notify your doctor promptly. Inform your doctor promptly if you develop:
muscle cramps, weakness, pain, nausea, vomiting. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include:
rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Tell your doctor your medical history, especially about:
gout, diabetes, liver problems, urinary problems, any allergies (especially to sulfa medications). Thiazide diuretics may increase sensitivity to sunlight. Avoid prolonged sun exposure. If you become sun sensitive, use a sunscreen and wear protective clothing when outdoors. This medication should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor. Thiazide diuretics appear in breast milk. Though there have been (to date) no reports of harm to nursing infants, consult your doctor before breast-feeding.

Inform your doctor about all the medicines you may use (both prescription and nonprescription), especially if you take:
lithium, digoxin, oral drugs used for diabetes, aspirin, NSAIDs (e.g., ibuprofen, naproxen), fluconazole. If you take colestipol or cholestyramine for High cholesterol, take the diuretic 1 hour before or 4 hours after because of decreased absorption into the bloodstream. Avoid any drugs that increase your heart rate or make you excited like decongestants because it may counter-act your blood pressure medicine. Decongestants are commonly found in over the counter cough-and-cold products. Ask your pharmacist if you are uncertain about decongestants in over-the-counter products. Do not start or stop any medicine without doctor or pharmacist approval.

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include unconsciousness, nausea/vomiting, weakness, slow or shallow breathing, dizziness, confusion, unusually slow heartbeat, seizures, drowsiness, or fainting.

Do not share this medication with others. This drug may reduce the potassium levels in your blood. Ask your doctor about increasing your dietary potassium. Salt substitutes contain potassium and may be beneficial. Sometimes a potassium supplement medication will be prescribed by your doctor.

If you miss a dose, take it as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not “double-up” the dose to catch up.

Store at room temperature away from moisture and sunlight. Do not store in the bathroom.

Johns Hopkins patient information

Copyright 1996-2014 Cerner Multum, Inc. Version: 16.02.
Revision date: July 8, 2011
Last revised: by Amalia K. Gagarina, M.S., R.D.

Drugs & Medications

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

The drug reference included in this section is provided by Cerner Multum, Inc., of Denver, Colorado. Armenian Medical Network receives monthly updates from Multum.