Trimipramine Maleate (Oral)

Trimipramine Maleate (By Mouth)

Trimipramine Maleate (trye-MI-pra-meen MAL-ee-ate)

Treats depression. Belongs to a class of drugs called tricyclic antidepressants.

Brand Name(s):
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to trimipramine or any other tricyclic antidepressant (such as Elavilreg;, Anafranilreg;, or Sinequanreg;). You should not take trimipramine if you have had a recent heart attack or have taken an MAO inhibitor drug (such as Parnatereg;, Nardilreg;, Marplanreg;) within the past 14 days.

How to Use This Medicine:

Tablet, Capsule

  • Your doctor will tell you how much medicine to take and how often.  
  • If you are taking trimipramine for depression, it may be several weeks before you feel better.

If a dose is missed:

  • Take the missed dose as soon as possible.  
  • If it is almost time for your next regular dose, wait until then to take your medicine and skip the missed dose.  
  • You should not use two doses at the same time.

How to Store and Dispose of This Medicine:

  • Store at room temperature in a closed container, away from heat, moisture, and direct light.  
  • Keep all medicine out of the reach of children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not drink alcohol while taking this medicine.  
  • Make sure your doctor knows if you are taking cimetidine (Tagametreg;) or any medicines that could make you sleepy such as sleeping pills, cold and allergy pills, other medicine for depression, tranquilizers, antihistamines, and strong pain killers.

Warnings While Using This Medicine:

  • If you are pregnant or breastfeeding, talk your doctor before taking this medicine.  
  • Be sure your doctor knows if you have heart or liver disease, seizures, glaucoma, thyroid problems, or problems with urination.  
  • Trimipramine may make you sleepy or dizzy. Be careful if driving a car or using machinery.  
  • This medicine may make your skin more sensitive to sunlight. Use a sunscreen when out doors. Avoid tanning beds and sunlamps.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Severe confusion or hallucinations  
  • Unexplained fever, chills, or sore throat  
  • Yellow skin or eyes  
  • Hives, rash, or swelling of face, lips, or tongue  
  • Difficulty going to the bathroom (urinating)  
  • Extreme excitement or irritability

If you notice these less serious side effects, talk with your doctor:

  • Drowsiness or dizziness  
  • Headache  
  • Dry mouth or blurred vision that does not go away after a few days  
  • Trembling or shakiness  
  • Nausea  
  • Weight gain

Johns Hopkins patient information

Copyright 1996-2014 Cerner Multum, Inc. Version: 16.02.
Revision date: July 3, 2011
Last revised: by David A. Scott, M.D.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

The drug reference included in this section is provided by Cerner Multum, Inc., of Denver, Colorado. Armenian Medical Network receives monthly updates from Multum.