Ticarcillin (Injection)

Ticarcillin (Injection)

Ticarcillin (tye-kar-SIL-in)

Treats infections caused by bacteria. Belongs to a class of drugs called penicillin antibiotics.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have ever had an allergic reaction to ticarcillin or any penicillin medicine.

How to Use This Medicine:


  • Your doctor will prescribe your exact dose and tell you how often it should be given.  
  • Keep using this medicine unless your doctor tells you to stop, even if you feel better. If you stop taking the medicine too soon, your infection may come back.  
  • An IM shot is given in your muscle (upper arm, thigh, buttocks)  
  • An IV is medicine that is put directly into your body through one of your veins.  
  • This medicine should be given by a person trained to give IM or IV medicine, such as a nurse. Sometimes you, family member, or friend can be taught to give your medicine.  
  • Check the IV bag to make sure there are no leaks. Also make sure the solution is clear.

If a dose is missed:

  • This medicine needs to be given on a regular schedule. Take the missed dose as soon as you remember. Take the rest of your doses for that day at evenly spaced times.  
  • Call your doctor for instructions if you miss more than one dose.

How to Store and Dispose of This Medicine:

  • If you see specks in the solution, you should not use it.  
  • Store the medicine in the refrigerator. Do not freeze.  
  • Take the medicine out of the refrigerator one hour before it is time for your next dose and allow it to warm to room temperature in a clean, dry place.  
  • If you have your treatments at home, you may be given a special container for the used needles. Keep it where children or pets cannot reach.  
  • Keep all medicine out of the reach of children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are taking probenecid (Benemidreg;, ColBENEMIDreg;) before you take ticarcillin.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you have ever had an allergic reaction to any type of medicine.  
  • Make sure your doctor knows if you have a bleeding disorder, kidney problems, intestinal disease (colitis), or hay fever or other allergies before you take this medicine.  
  • If your infection does not improve, or if it gets worse while taking this medicine, talk to your doctor.  
  • If this medicine gives you severe diarrhea, check with your doctor before taking medicine to stop the diarrhea.  
  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Rash or hives, blistering or peeling skin  
  • Swelling of the face, throat, or lips  
  • Wheezing or trouble breathing  
  • Severe diarrhea (watery or bloody)  
  • Swelling, pain, or redness where your IV or shot is given  
  • Unusual bleeding or bruising  
  • Extreme weakness, muscle cramps

If you notice these less serious side effects, talk with your doctor:

  • Mild diarrhea or nausea  
  • Sore mouth or tongue  
  • Vaginal itching or discharge

If you notice other side effects that you think are caused by this medicine, tell your doctor.

Johns Hopkins patient information

Copyright 1996-2014 Cerner Multum, Inc. Version: 16.02.
Revision date: June 22, 2011
Last revised: by Amalia K. Gagarina, M.S., R.D.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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