Ticarcillin/Clavulanic Acid (Injection)

Ticarcillin/Clavulanic Acid (Injection)

Clavulanic Acid (klav-yoo-LAN-ik AS-id), Ticarcillin (tye-kar-SIL-in)

Treats infections caused by bacteria. This medicine is an antibiotic.

Brand Name(s):

Timentin, Timentin Novaplus
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to ticarcillin/clavulanic acid or any penicillin medicine.

How to Use This Medicine:


  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.  
  • A nurse or other trained health professional will give you this medicine. It may also be given by a home health caregiver.  
  • You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.  
  • Use a new needle and syringe each time you inject your medicine.  
  • Never share your medicine with anyone.

If a dose is missed:

  • If you miss a dose or forget to use your medicine, call your doctor, home health caregiver, or pharmacist for instructions.

How to Store and Dispose of This Medicine:

  • Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container out of the reach of children and pets.  
  • If you store this medicine at home, keep it at room temperature, away from heat and direct light. Do not freeze. Ask your caregiver how long you can store the medicine.  
  • Keep all medicine out of the reach of children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using probenecid.  
  • Tell your doctor if you are on a low-salt diet.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, electrolyte problems (such as high or low potassium or calcium in your blood), or a stiff neck or severe headache.  
  • Tell your doctor if you have ever had an allergic reaction to a cephalosporin antibiotic (such as Ceftinreg;, Cephalexinreg;, Keflexreg;, or Ceclorreg;) and about any other allergies you have.  
  • If your symptoms do not improve or if they get worse, call your doctor.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing  
  • Severe skin blistering, peeling, redness, or other rash  
  • Muscle weakness or twitching, irregular heartbeat  
  • Seizures, convulsions  
  • Severe diarrhea (watery or bloody), nausea, stomach cramps or bloating (may happen after you stop using Timentinreg;)  
  • Swelling, pain, or redness where the needle is inserted  
  • Unusual bleeding or bruising

If you notice these less serious side effects, talk with your doctor:

  • Mild diarrhea, nausea, gas

If you notice other side effects that you think are caused by this medicine, tell your doctor.

Johns Hopkins patient information

Copyright 1996-2014 Cerner Multum, Inc. Version: 16.02.
Revision date: July 3, 2011
Last revised: by Dave R. Roger, M.D.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

The drug reference included in this section is provided by Cerner Multum, Inc., of Denver, Colorado. Armenian Medical Network receives monthly updates from Multum.