Tetanus Toxoid/Diphtheria Toxoid, Adsorbed (Vaccine) (Injection)

Tetanus Toxoid/Diphtheria Toxoid, Adsorbed (Vaccine) (Injection)

Diphtheria Toxoid, Adsorbed (dif-THEER-ee-a TOX-oyd, ad-SORB-ed), Tetanus Toxoid (TET-n-us TOX-oyd)

Protects against infections caused by tetanus (lockjaw) and diphtheria.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

Do not have this vaccine if you have ever had an allergic reaction to tetanus or diphtheria vaccine, or to thimerosal. This vaccine should not be used if you have an infection with fever.

How to Use This Medicine:


  • An IM shot is given in your muscle, usually in your shoulder muscle.  
  • The doctor or nurse will give you this shot.  
  • You will probably have redness and swelling around the area where your shot is given. This is common and usually goes away after a couple of days.  
  • You will need to get a “booster” shot 4 to 8 weeks after your first shot, and again 6 to 12 months later.  
  • After your first set of shots, you should get one booster shot every 10 years.

If a dose is missed::

  • Try not to miss a dose.  
  • Make another appointment to have your shot as soon as possible if you miss a dose.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are taking corticosteroid medicine such as prednisone.

Warnings While Using This Medicine:

  • If you are pregnant or breastfeeding, talk to your doctor before receiving this vaccine.  
  • Before getting this vaccine, make sure your doctor knows if you have a bleeding disorder or if you have ever had a seizure caused by high fever.  
  • This vaccine may not work as well if you have a bone marrow disorder, if you are HIV positive, or if you are receiving anti-cancer medicines.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Seizures  
  • Skin rash, hives, itching  
  • Wheezing or trouble breathing  
  • Swelling of the lips, face, or tongue  
  • Fever of 103° F or more

If you notice these less serious side effects, talk with your doctor:

  • Redness, swelling, or a lump where the shot was given that does not go away after a few days  
  • Fever below 103° F with drowsiness or swollen glands

Johns Hopkins patient information

Copyright 1996-2014 Cerner Multum, Inc. Version: 16.02.
Revision date: July 8, 2011
Last revised: by David A. Scott, M.D.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

The drug reference included in this section is provided by Cerner Multum, Inc., of Denver, Colorado. Armenian Medical Network receives monthly updates from Multum.