Rh0 [D] Immune Globulin

Rh0 [D] Immune Globulin injection

What is Rh0 [D] immune globulin injection?
Rh0 [D] IMMUNE GLOBULIN (BayRho-D™, MICRhoGAM®, RhoGAM®, and WinRho SDF™) is administered to women who are pregnant with a child that does not have a blood type (Rh factor) that is compatible to the mother’s. Rh0 [D] immune globulin is used to prevent the mother from reacting to the baby’s blood. Rh0 [D] immune globulin is also given to some patients who are infused with incompatible blood products. Rh0 [D] immune globulin helps individuals with a blood disease called idiopathic thrombocytopenic purpura (ITP) to maintain proper platelet counts and avoid problems related to the condition. Rh0 [D] immune globulin injections are available from many manufacturers.

What should my health care professional know before I receive Rh0 immune globulin?
They need to know if you have any of these conditions:

  • bleeding disorders
  • blood disease
  • spleen removed
  • immunoglobulin A deficiency
  • an unusual or allergic reaction to immune globulin, human immunoglobulin, thimerosal, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?
Rh0 [D] immune globulin is for injection into a muscle or into a vein. It is given by a health-care professional in a hospital or clinic setting.

What if I miss a dose?
Depending on your condition, you may need several Rh0 [D] immune globulin treatments. For the best protection, try to keep these appointments at the proper intervals as directed by your health care professional. If you miss an appointment, call to reschedule the appointment as soon as possible.

What drug(s) may interact with Rh0 [D] immune globulin?

  • live virus vaccines

If any of these vaccines are administered during or within 3 months after Rh0 [D] immune globulin, the vaccines may not be as effective at preventing illness. Ask your health care professional about the changes that may need to occur in your immunization schedule.

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from receiving Rh0 [D] immune globulin?
Side effects that you should report to your prescriber or health care professional as soon as possible:

  • difficulty breathing, shortness of breath, coughing, or wheezing
  • chest pain or tightness
  • unusual skin rash or bruising
  • swelling of the eyes or face

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

  • fever
  • headache
  • muscle aches and pains
  • pain and tenderness at the injection site

What should I watch for while taking Rh0 [D] immune globulin?
Because this product is developed from pooled blood samples of many different donors, it is theoretically possible that viruses or bacteria could be transmitted in the product. Since 1985, however, all products are tested for HIV and hepatitis, and all products undergo processing to reduce the risk of infection.

Where can I keep my medicine?
Each dose of this medicine will be administered in the clinic or office of a health care professional. You will not be given RSV immune globulin doses to store at home.

Johns Hopkins patient information

Copyright 1996-2014 Cerner Multum, Inc. Version: 16.02.
Revision date: June 22, 2011
Last revised: by Sebastian Scheller, MD, ScD

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