Buspirone

What is Buspirone?
Buspirone (Buspirone) is used to reduce fear, tension, and anxiety associated with anxiety disorders. Buspirone is an anti-anxiety medicine. Buspirone affects chemicals in your brain that may become unbalanced and cause anxiety.

COMMON MISSPELLINGS
This list below outlines common misspellings of Buspirone.

  * Busper, Bespar, Busspar, and Buspirones

What are the side effects of Buspirone?
If you experience any of the following serious side effects, stop taking Buspirone and seek emergency medical attention: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; hives); chest pain or an irregular heartbeat; headache, dizziness, lightheadedness, slurred speech, confusion, or blurred vision; numbness or tingling in your hands, feet, arms, or legs; depression; or uncontrollable movements of your arms, legs, tongue, or lips. Other, less serious side effects may be more likely to occur. Continue to take Buspirone and talk to your doctor if you experience drowsiness or fatigue, dry mouth, or an increase in nightmares or dreams.

How do I take Buspirone?
Take each dose with a full glass of water.

What if I miss a dose?
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.

Are there any drug interactions with Buspirone?
Do not take Buspirone if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) during the last 2 weeks. Severely high blood pressure may occur if Buspirone is taken with a monoamine oxidase inhibitor. Before taking Buspirone, tell your doctor if you are taking any of the following medicines: nefazodone (Serzone); itraconazole (Sporanox); erythromycin (E-Mycin, E.E.S., Ery-Tab, Eryc, others); or selegiline (Eldepryl).

Is there any additional information about Buspirone that I should know?
Do not take Buspirone if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) during the last 2 weeks. Severely high blood pressure may occur if Buspirone is taken with a monoamine oxidase inhibitor. Before taking Buspirone, tell your doctor if you have had an allergic reaction to Buspirone in the past; have taken a monoamine oxidase inhibitor such as phenelzine (Nardil), isocarboxazid (Marplan), or tranylcypromine (Parnate) within the last 14 days; have kidney disease; have liver disease; have a history of alcohol or drug addiction.  It may be several weeks before you start to feel better, but do not stop taking Buspirone without first talking to your doctor. Grapefruit and grapefruit juice may interact with Buspirone. The interaction could lead to potentially adverse effects. You should discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Buspirone may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any prescription or over-the-counter medicine without first talking to your doctor. Buspirone passes into breast milk and may affect a nursing infant. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How do I store Buspirone?
Store Buspirone at room temperature away from moisture and heat.  Always keep all prescription medications out of the reach of children.

Johns Hopkins patient information

Copyright 1996-2014 Cerner Multum, Inc. Version: 16.02.
Revision date: June 21, 2011
Last revised: by Janet A. Staessen, MD, PhD

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