Bosentan (By Mouth)
Treats a lung condition called pulmonary arterial hypertension.
There may be other brand names for this medicine.
When This Medicine Should Not Be Used:
You should not use this medicine if you have had an allergic reaction to bosentan, if you are pregnant, or if you are also using cyclosporine (Neoralreg;, Sandimmunereg;), or glyburide (Diabetareg;, Micronasereg;).
How to Use This Medicine:
- Your doctor will tell you how much of this medicine to take and how often. Do not take more medicine or take it more often than your doctor tells you to.
- You may take this medicine with or without food.
- Never share your medicine with anyone.
If a dose is missed:
- If you miss a dose or forget to take your medicine, take it as soon as you can. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose.
- Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine:
- Store the medicine at room temperature, away from heat, moisture, and direct light.
- Keep all medicine away from children.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are also using ketoconazole (Nizoralreg;), blood thinners (warfarin, Coumadinreg;), medicine to lower cholesterol (such as Baycolreg;, Lescolreg;, Lipitorreg;, Mevacorreg;, Pravacholreg;, Zocorreg;).
Warnings While Using This Medicine:
- Using this medicine while you are pregnant can harm your unborn baby. Use two forms of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
- Make sure your doctor knows if you are breastfeeding, or if you have liver or kidney disease.
- Do not stop using this medicine suddenly without asking your doctor. You may need to slowly decrease your dose before stopping it completely.
- Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing
- Dark-colored urine or pale stools
- Fast or pounding heartbeat
- Lightheadedness or fainting
- Nausea, vomiting, loss of appetite, pain in the upper stomach
- Swelling in your ankles or feet
- Warmth or redness in the face, neck, arms, or upper chest
- Yellow skin or eyes
If you notice these less serious side effects, talk with your doctor:
- Upset stomach
Revision date: July 5, 2011
Last revised: by Sebastian Scheller, MD, ScD
Drugs & Medications
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
The drug reference included in this section is provided by Cerner Multum, Inc., of Denver, Colorado. Armenian Medical Network receives monthly updates from Multum.