Smoking Cessation More Successful for Cancer Patients Who Quit Before Surgery, Moffitt Cancer Center Researchers Say

Lung and head and neck cancer patients who smoked before surgery are more likely to relapse than those who had quit before surgery, Moffitt Cancer Center researchers say. They found that smoking-relapse prevention interventions are needed immediately after surgery to help prevent relapse.

The study was published in a recent issue of the journal Cancer.

“Cigarette smoking is responsible for 30 percent of all cancer-related mortalities,” said study corresponding author Vani Nath Simmons, Ph.D., assistant member of the Health Outcomes and Behavior Program at Moffitt. “Head and neck and lung cancers are the most strongly linked to tobacco use. Many patients with these cancers make an attempt to quit smoking at the time of diagnosis.  However, little attention has been paid to looking at how successful patients are at quitting and what predicts who is likely to resume smoking. This is particularly a concern for cancer patients because continued smoking can be related to cancer recurrence, cancer treatment complications, second primary tumors and poorer quality of life.”

According to study co-author Thomas H. Brandon, Ph.D., director of the Tobacco Research and Intervention Program at Moffitt, “Only a few studies have examined factors associated with smoking relapse among patients with head and neck cancer or lung cancer, and this information is needed to develop smoking-relapse prevention interventions for this population.”

The goal of this study is to examine smoking trajectories among lung and head and neck cancer patients for 12 months after surgery and to test potential predictors of smoking relapse.

Study participants were recruited from clinics at Moffitt. Patients had either quit smoking shortly before or immediately after surgery. Smoking behavior was assessed at two, four, six and 12 months after surgery.

Smoking cessation can seem like an elusive goal, but plenty of people have been able to quit and become comfortable ex-smokers who never miss their old smoking habit.  As smokers, this is what we all dream of achieving.  We hope that we’ll be able to say goodbye to nicotine addiction and never look back.

Ready to Quit
Eventually, there comes a time for most smokers when the “smokescreen” starts to wear thin. And when it does, smoking loses its luster; its ability to soothe. Instead, smoking becomes a fearful, anxiety-ridden activity that has little to do with pleasure or relaxation, and we find ourselves thinking about quitting with every cigarette we light.

The fact that you’re here reading this article is a good sign. You’re probably sick of smoking, and unhappy enough to be seeking out some help. Good for you, because when it comes to overcoming the addiction to nicotine, education is key. The more you understand about how smoking affects you and what to expect as you wean yourself away from it, the better prepared you’ll be for success.

Why do you want to quit smoking?
What are the reasons behind your desire to quit smoking? Sit down with paper and pen, and list them out. Include every single thing you can think of, from the largest, most obvious of reasons, to the smallest.

“We found that relapse rates varied significantly depending on a patient’s pre-surgery smoking status,” Simmons explained. “Sixty percent of patients who smoked during the week prior to surgery resumed smoking afterward, contrasted with a 13 percent relapse rate for those who had quit smoking prior to surgery.”

Given the significantly lower relapse rates among those who quit smoking prior to surgery, smoking cessation should be encouraged at diagnosis, the researchers said. Because most relapses occurred shortly after surgery, they recommend that smoking cessation assistance is important before and after surgery

A Few Alarming Facts…

  Smoking has been identified as the single most preventable cause of death and disease in the United States.
  Cigarettes currently cause approximately 20% of all deaths in the U.S.
  Approximately 50 million Americans smoke.
  Each year, about 3 million people worldwide die from smoking, with about one-third coming from developing countries.

The researchers also found that factors such as high fears regarding cancer recurrence, greater proneness to depression, and less belief in their ability to quit smoking predicted smoking relapse.

“Cancer patients are highly motivated to quit, so receiving a cancer diagnosis can be viewed as a ‘teachable moment’ for delivering smoking cessation and relapse prevention interventions,” Brandon said.

“Cancer patients need to know that it’s never too late to quit,” Simmons said.  “Of course, it would be best if they quit smoking before getting cancer; but barring that, they should quit as soon as they get diagnosed.  And with a little assistance, there is no reason that they can’t succeed.”

Funding for this study was provided for by a National Cancer Institute grant R0 CA 126409 and the Miles for Moffitt Foundation.

About Moffitt Cancer Center

Located in Tampa, Moffitt is one of only 41 National Cancer Institute-designated Comprehensive Cancer Centers, a distinction that recognizes Moffitt’s excellence in research, its contributions to clinical trials, prevention and cancer control. Since 1999, Moffitt has been listed in U.S. News & World Report as one of “America’s Best Hospitals” for cancer. With more than 4,200 employees, Moffitt has an economic impact on the state of nearly $2 billion.


H. Lee Moffitt Cancer Center & Research Institute

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