Course and subtypes of schizophrenia

Both ICD-10 and DSM-IV provide broadly similar classifications of longitudinal course.  The subtypes of schizophrenia included in both ICD-10 and DSM-IV are paranoid, catatonic, undifferentiated and residual schizophrenia.  Hebephrenic schizophrenia is called disorganized type in DSM-IV.  The requirement for the subtypes is similar in both classification systems,  although they are more clearly operationalized in DSM-IV.

Common subtypes in ICD-10 and DSM-IV
•  Paranoid
•  Catatonic
•  Hebephrenic (disorganized in DSM-IV)
•  Residual
•  Undifferentiated


Additional subtypes in ICD-10
•  Simple
•  Postschizophrenic depression

ICD-10 also includes subcategories of simple schizophrenia and postschizophrenic depression as subtypes of schizophrenia.

ICD-10 clarifies retention of simple schizophrenia as a subtype of schizophrenia,  with the requirement of certain described features for at least 2 years because of its continued use in some countries and because of the uncertainty about its nature, which will require additional information for resolution.


Table 1.4 DSM-IV diagnostic criteria for schizophrenia.
Characteristic symptoms
At least one of:
  Bizarre delusions
  Third person auditory hallucinations
  Running commentary

or two or more of:
  Delusions
  Hallucinations
  Disorganized speech
  Grossly disorganized behaviour
  Negative symptoms

Duration
1 month of characteristic symptoms
With 6 months of social/occupational dysfunction

Exclusion criteria
Schizoaffective or mood disorders
Direct consequence of substance use or general medical condition
Pervasive developmental disorders

Diagnosis of postpsychotic depression requires a clear diagnosis of schizophrenia within the past 12 months with the presence of some features of schizophrenia and predominant depressive symptoms, which meet a threshold of depressive episode, for 2 weeks.

In addition to a categorical description of schizophrenia subtypes, DSM-IV offers a dimensional alternative in its Appendix B:

  • psychotic dimension;
  • disorganized dimension; and
  •   negative dimension.

ICD-10 does not give a description of any dimensions yet as these are difficult to define.

J.K. Wing and N. Agrawal

Edited by
Steven R. Hirsch
MD FRCP FRCPsych
Professor of Psychiatry Emeritus, Division of Neuroscience and Psychological Medicine Imperial College Faculty of Medicine and Director of Teaching Governance, West London Mental Health NHS Trust London, UK


Daniel R. Weinberger MD
Chief, Clinical Brain Disorders Branch Intramural Research Program National Institute of Mental Health Bethesda MD 20982, USA

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