It is generally accepted that the first building block of modern psychiatric nosology was Kraepelin’s distinction between those disorders we now know as mood disorders and the illness (or illnesses) we…

Figure 2­1 depicts an integrative schema that conceptualizes the interplay of extrinsic and intrinsic factors with the schizophrenia diathesis. The basis for this formulation is the familiar stress-diathesis model…

An appropriate treatment approach to depression begins with a consideration of the differential diagnostic possibilities outlined earlier in this chapter. Obviously, since there are no available biological tests (except for the medical/organic conditions), or even…

More than two dozen studies have been published examining the rates of occurrence of depression in the course of schizophrenia (Koreen et al. 1993; Sands and Harrow 1999;…