Women lose weight at least a decade before developing dementia

	Tweet

Women who have dementia start losing weight at least 10 years before the disease is diagnosed, according to a study published in the August 21, 2007, issue of Neurology®, the medical journal of the American Academy of Neurology.

The researchers examined the records of 481 people with dementia and compared them to 481 people of the same age and gender who did not have dementia. The average weight was the same for those in the two groups from 21 to 30 years before the year the disease was diagnosed. But the women who would later develop dementia started losing weight up to 20 years before the disease was diagnosed. On average, those with dementia weighed 12 pounds less than those without the disease the year the disease was diagnosed.

“One explanation for the weight loss is that, in the very early stages of dementia, people develop apathy, a loss of initiative, and also losses in the sense of smell,” said study author David Knopman, MD, of the Mayo Clinic in Rochester, MN, and member of the American Academy of Neurology. “When you can’t smell your food, it won’t have much taste, and you might be less inclined to eat it. And, apathy and loss of initiative may make women less likely to prepare nutritious meals and more likely to skip meals altogether.”

Unlike women, men in this study who later developed dementia did not lose weight in the years before diagnosis. Knopman said the difference could be due to hormones, but a social reason seems just as likely.

“Middle-aged and elderly men are less likely to be preparing their own meals,” he said. “Their spouses or adult children were more likely making meals for them, which would lessen the effect of the apathy, loss of initiative and loss of sense of smell.”

The study conflicts with others suggesting that obesity in middle-age may be a risk factor for dementia. Obesity is also associated with diabetes, hypertension, and cardiovascular disease, which are risk factors for dementia. “We’ll need to do more research to look into these differences,” Knopman said.
###

The study was supported by grants from the National Institute on Aging.

The American Academy of Neurology, an association of more than 20,000 neurologists and neuroscience professionals, is dedicated to improving patient care through education and research. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as stroke, Alzheimer’s disease, epilepsy, Parkinson’s disease, and multiple sclerosis.

Contact: Angela Babb

651-695-2789
American Academy of Neurology

RELATED STORIES:
Weight in pregnancy best controlled by diet, study shows   FDA advisers recommend approving weight loss drug   Bridal Hunger Games   Exercise, Group Support Work for Weight Loss   Misperception of weight is an important barrier to weight loss   Obesity drugs need heart studies, U.S. advisers say   Weight Loss Surgery and Diabetes: Expert Interview Opportunity   New evidence on effects of green coffee beans in weight loss   Chocolate lovers tend to weigh less: study   Weight loss won’t necessarily help teen girls’ self-esteem   How to Best Help Your Child Lose Weight: Lose Weight Yourself   Qnexa: Is the new anti-obesity drug too risky?

Comments

[ + Post Your Own ]

Now you're in the public comment zone. What follows is not Armenian Medical Network's stuff; it comes from other people and we don't vouch for it. A reminder: By using this Web site you agree to accept our Terms of Service. Click here to read the Rules of Engagement.

There are no comments for this entry yet. [ + Comment here + ]