Health news
Health news top Health news

   Login  |  Register    
Health News Make AMN Your Home PageDiscussion BoardsAdvanced Search ToolMedical RSS/XML News FeedHealth news
  You are here : Health.am > Health Centers > Sexual healthSexual Health News

Men have a biological clock too and produce poor quality sperm as they age

Sexual Health NewsJun 06, 2006

Researchers in the U.S. say that even though men are able to father children well into old age, the quality of the sperm declines as men age.

It seems not only does the sperm lose their ability to swim in a straight line they also become genetically defective.

These latest results support other recent studies which have found that men become less fertile and also tend to have more children with birth defects as they age.

The study was led by scientists at Lawrence Livermore National Laboratory (LLNL) and the University of California, Berkeley.

Andrew Wyrobek co- lead author says it shows that men who wait until they’re older to have children are not only risking difficulties conceiving, they could also be increasing the risk of passing along dwarfism and other genetic diseases to their children.

The apparent increase in birth defects with aging has traditionally been attributed to women, whose fertility drops considerably with age and disappears totally at menopause.

Women are born with all their eggs and as they age the egg cells mature and ripen and older eggs are often defective.

This affects female fertility and creates the likelihood of genetic defects such as Down syndrome.

Older women are known to have an increased risk for infertility, spontaneous abortion, and genetic and chromosomal defects in pregnancy but the affects of male aging is less well researched say the researchers.

The research suggests that men also have a biological time clock.

For the study, the researchers analyzed DNA damage, chromosomal abnormalities and gene mutations in semen samples from 97 healthy, non-smoking LLNL employees and retirees between 22 and 80 years old by using a variety of state-of-the art methods for detecting defects in human sperm.

The researchers gathered extensive medical, lifestyle and occupational exposure history from the men and disqualified from the study those who were cigarette smokers and men with current fertility or reproductive problems or who had undergone chemotherapy or radiation treatment for cancer.

They then examined the sperm for features such as the ability to swim quickly, and also for DNA fragmentation, which is a measure of damage linked with male fertility, successful conception, and sustained pregnancy.

The researchers found that men usually started to have an abnormal DNA fragmentation index at the age of 56 and they say that their findings provide further evidence that men choosing to delay fatherhood may have a lower likelihood of a successful pregnancy free of early loss and gene defects.

But they also found that there did not appear to be a reliable test for healthy sperm and men with apparently good semen could still be at risk of fathering a child with a genomic defect.

The study also identified a small number of men who may be at increased risk for transmitting multiple genetic and chromosomal defects.

They say it is important to understand the effects of men having children at ever-older ages as increasing numbers of older men are having children.

Since 1980 there has apparently been a 40 percent increase in 35- to 49-year-old men fathering children, and a 20 percent decrease in fathers under 30.

Earlier studies have also shown that it takes longer for older men to conceive, even when the age of the mother is considered.

###

The report is published in the current issue of the Proceedings of the National Academy of Sciences.

###

SOURCE: BJU International

Provided by ArmMed Media
Revision date: Sept. 19, 2012
Last revised: by Alexander D. Davtyan, M.D

Email this to a friend Bookmark this! Printable Version

RELATED STORIES:


 Comments [ + Post Your Own

Now you're in the public comment zone. What follows is not Armenian Medical Network's stuff; it comes from other people and we don't vouch for it. A reminder: By using this Web site you agree to accept our Terms of Service. Click here to read the Rules of Engagement.

There are no comments for this entry yet. [ + Comment here + ]




We are pleased to let readers post comments about an article. Please increase the credibility of your post by including your full name and email.

All comments are reviewed by our editors before they are posted on the site. Just keep it clean, kids.

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

   [advanced search]   
Top Erectile Dysfunction Drugs
Viagra | Levitra | Cialis
Interactive Quiz:
1. The most common form of contraception used by couples in the United States is
Pills
Condom
Diaphragm
Intrauterine device (IUD)
Permanent sterilization
Most Searched:
Erectile Dysfunction
Causes of ED
Penile Prosthesis
Male Sexual Dysfunction
Most Viewed:
Premature Ejaculation
Vaginismus
Erectile Disorder
Pedophilia
Transvestism
Premature Ejaculation
Gender Identity Disorder of Adulthood
Paraphilias and Paraphilia-Related Disorders



Health Centers

  Contraception

  Male Infertility

  Erectile Dysfunction

  Male Sexual Dysfunction

  Sexual and Gender
  Identity Disorders


  Sexual Desire Disorders

  Male Erectile Disorder

  Female Sexual Arousal
  Disorder and Female
  Orgasmic Disorder


  Premature Ejaculation and
  Male Orgasmic Disorder


  Sexual Pain Disorders

  Paraphilias and
  Paraphilia-Related Disorders


  Pedophilia

  Transvestism and Gender
  Identity Disorder in Adults


  Gender Identity Disorder in
 Children and Adolescents


» » »


  Sexually Transmitted
  Infections


  Bacterial Infections

   - Neisseria Gonorrhoeae

   - Chlamydia Trachomatis

   - Treponema Pallidum

  Protozoan and
  Fungal Infections


   - Candida Albicans

   - Trichomonas Vaginalis

  Viral Infections

   - Introduction

   - Human Papillomavirus

  Sexually Transmitted
  Disease Syndromes


   - Bacterial Vaginosis

   - Pelvic Inflammatory
   - Disease


   - Epididymitis

   - Proctitis

Health Centers





Diabetes









Health news
  


Health Encyclopedia

Diseases & Conditions

Drugs & Medications

Health Tools

Health Tools



   Health newsletter

  





   Medical Links



   RSS/XML News Feed



   Feedback






Sexual health News, Headlines and Latest Stories on Health.am
Add to My AOL

Add to Google Reader or Homepage