Much of the improved survival for patients with HIV infection in recent years owes to the prevention of PCP. Hence, the use of antipneumocystis agents such as trimethoprim-sulfamethoxazole, dapsone,…

Pneumocystis carinii Pneumonia
PCP is the most common lung disease in persons with advanced HIV infection. The presentation tends to be indolent, characterized by slowly progressive shortness of breath…

Although the differential diagnosis of lung disease in a person with HIV infection is quite broad, the probabilities of the various diagnoses can be reduced in a given patient by knowing the…

Disorders Not Necessarily Associated with Severe Immune Suppression

Bronchitis
Acute bronchitis in the PCHIS was defined by the presence of cough with sputum production for at…

Relationship of respiratory tract diseases to CD4+ Lymphocyte count, Demographic Characteristics, and Transmission Category

PCP is the most common lung disease in persons with CD4+ counts…

The conceptual relationship between the frequency and spectrum of lung diseases and CD4+ lymphocyte count is shown in Figure 412-1. The data that support this concept have…

The hallmark of the effect of HIV infection on host immune response is a progressive reduction in the number of circulating CD4+ lymphocytes or “T-helper” cells. The CD4+ lymphocyte plays…

Philip C. Hopewell

Lung disease, specifically Pneumocystis carinii pneumonia (PCP), was the first recognized mode of expression of infection with the human immunodeficiency virus (HIV). Since the original clusters of…