Ziagen
Key points
- This drug can cause severe, even fatal, allergic reactions, liver problems, and blood acid-base balance (lactic acidosis) problems.
- This medication is used to treat HIV infection in combination with other anti-HIV medications.
- Take this medication by mouth as directed, generally twice daily with or without food.
- If these effects persist or worsen, notify your doctor.
ABACAVIR - ORAL (uh-BACK-uh-veer)
COMMON BRAND NAME(S):
Ziagen
WARNING:
This drug can cause severe, even fatal, allergic reactions, liver problems, and blood acid-base balance (lactic acidosis) problems. If you develop symptoms such as rash, fever, fatigue, difficult or rapid breathing, cough, throat inflammation, dark urine, yellowing of the skin or eyes, drowsiness, muscle aches, stomach/abdominal pain, nausea, vomiting, or diarrhea immediately stop using this medication and notify your doctor. Do not restart this medication if an allergic reaction to this drug has occurred because more severe, life-threatening problems could occur (including low blood pressure and death). Also, if an allergic reaction is only suspected, this medication should never be restarted. (See precautions regarding stopping and starting this medication.) It is not known how long this drug will benefit those with HIV infection.
USES:
This medication is used to treat HIV infection in combination with other anti-HIV medications.
HOW TO USE THIS MEDICATION:
Take this medication by mouth as directed, generally twice daily with or without food. Dosage is based on your condition and response to therapy. Read the Medication Guide provided by your pharmacist. Carry the "Warning Card" with you at all times. It is very important to continue taking this medication and other anti-HIV medications exactly as prescribed by your doctor. Do not skip any doses.
SIDE EFFECTS:
Headache and trouble sleeping may occur. If these effects persist or worsen, notify your doctor. Very unlikely but report promptly dark urine, yellowing eyes/skin, rapid breathing or a change in amount of urine. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction to this drug include fever, nausea, vomiting, diarrhea, skin rash, extreme tiredness, achiness, stomach pain, swelling, trouble breathing, cough or sore throat. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS:
Tell your doctor your medical history, including any allergies, liver disease, alcohol dependence and diabetes. Limit alcohol intake, as it may intensify side effects of this drug. If you must stop using this drug due to an allergic reaction, never use the drug again or death could result. Consult MD and read the "Warning Card" for more details. If you stop using abacavir (e.g., forget to order a refill) even for a short time and then restart the drug, you have an increased chance of developing the very serious (possibly fatal) allergic reaction. Do not stop treatment unless specifically instructed to do so. Know the symptoms of this allergic reaction (see side effects section). Consult your doctor or pharmacist before restarting abacavir, and be sure you have easy access to medical care if you are restarting treatment. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into breast milk. Avoid breast-feeding because breast milk can transmit HIV. Consult your doctor or pharmacist before breast-feeding.
Written and revised by
David Cohen, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.

