Zerit
Key points
- Severe, even fatal, liver and blood acid-base balance problems (lactic acidosis) have occurred while using this medication.
- This medication is used in combination with other medication(s) to treat HIV infection.
- Take this medication by mouth exactly as prescribed, usually twice a day.
- The most common side effect of this medication is peripheral neuropathy (nerve disorder).
STAVUDINE - ORAL CAPSULE (STAV-you-deen)
COMMON BRAND NAME(S):
Zerit
WARNING:
Severe, even fatal, liver and blood acid-base balance problems (lactic acidosis) have occurred while using this medication. Fatal lactic acidosis has also occurred during pregnancy when this medication was used in combination with didanosine and other drugs used to treat HIV. Notify your doctor immediately if you develop dark urine, yellowing of the skin or eyes, abdominal or stomach pain, rapid breathing, drowsiness, or muscle aches. When used in combination with certain medicines, pancreatitis (sometimes fatal) has occurred on rare occasions. Notify your doctor immediately if you develop severe stomach/abdominal pain.
USES:
This medication is used in combination with other medication(s) to treat HIV infection. Stavudine is not a cure for HIV and does not prevent the passing of HIV to others.
HOW TO TAKE THIS MEDICATION:
Take this medication by mouth exactly as prescribed, usually twice a day. For best effects, space the doses at even intervals throughout the day (and night if directed by your doctor). This will help ensure an even level of drug in the body at all times. Ask your doctor or pharmacist to help devise a dosing schedule best for you. Do not increase your dose or take this more often than directed. Your condition will not improve faster but the risk of side effects may be increased.
SIDE EFFECTS:
The most common side effect of this medication is peripheral neuropathy (nerve disorder). Symptoms of peripheral neuropathy are numbness, tingling, burning or pain of the hands or feet. Notify your doctor if you develop any of these. Headache, diarrhea or nausea or loss of appetite may occur. If any of these effects persist or worsen, notify your doctor promptly. Notify your doctor if any of these serious side effects occur:
chills, fever, sore throat, itch, rash, muscle aches, trouble sleeping, unusual bleeding or bruising, stomach pain, yellowing of the eyes and skin, dark urine, rapid breathing. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include:
rash, itching, swelling, dizziness, breathing trouble. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS:
Tell your doctor your medical history, especially of:
kidney or liver diseases, pancreatitis, nerve disease, heart disease, major injury/surgery/infection, alcohol usage, any allergies. This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this medication appears in human breast milk. Avoid breast-feeding in order to protect the newborn from possible HIV transmission.
Written and revised by
Andrey Nailor, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.

