Epinephrine
Key points
- EPINEPHRINE (Epifrinreg;, Epinalreg;, Eppy/Nreg;) may be used during eye surgery or to treat certain kinds of glaucoma.
- Epinephrine eye solution is only for use in the eye; do not take by mouth.
- If it is almost time for your next dose, use only that dose.
- Tell your prescriber or health care professional about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products.
Epinephrine eye solution
What is epinephrine eye solution? EPINEPHRINE (Epifrinreg;, Epinalreg;, Eppy/Nreg;) may be used during eye surgery or to treat certain kinds of glaucoma. Generic epiniphrine eye solutions are available.
What should my health care professional know before I use epinephrine?
They need to know if you have any of the following conditions:
- blood vessel disease
- brain damage or disease
- diabetes
- glaucoma
- heart disease
- high blood pressure
- over active thyroid
- an unusual or allergic reaction to epinephrine, sulfites, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
- breast-feeding
How should I use this medicine?
Epinephrine eye solution is only for use in the eye; do not take by mouth. Follow the directions on the prescription label. Wash hands before and after use. With your middle finger, apply pressure to the inside corner of your eye for 1 to 2 minutes before use and for 2 to 3 minutes after use. Tilt your head back and pull your lower eyelid down with a finger to form a pouch. Squeeze the required number of drops into the pouch. Do not blink for 30 seconds. Close your eye gently for 1 to 2 minutes until the solution is completely absorbed, keeping the pressure on the corner of your eye. Do not touch your eye or surrounding tissue with the eye dropper. You may feel a slight tingling in your eye shortly after applying the drops, but this effect should go away quickly. Do not use your medicine more often than directed.
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.
What drug(s) may interact with epinephrine?
- beta-blockers, often used for high blood pressure or heart problems
- bromocriptine
- heart medicine (such as digoxin, digitoxin)
- linezolid
- medicines for colds and breathing difficulties
- medicines for hay fever and other allergies
- medicines for high blood pressure
- medicines for mental depression
- medicines for migraine
Written and revised by
Andrey Nailor, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.

