Butorphanol
Key points
- BUTORPHANOL (Stadolreg;) relieves moderate to severe pain.
- Butorphanol is for injection into a muscle or a vein.
- Because butorphanol can cause drowsiness, other medicines that also cause drowsiness may increase this effect of butorphanol.
- Tell your prescriber or health care professional if your pain does not go away, if it gets worse, or if you have new or different type of pain.
Butorphanol injection
What is butorphanol injection? BUTORPHANOL (Stadolreg;) relieves moderate to severe pain. Butorphanol decreases the pain of migraine headaches, and labor and delivery. It can help to supplement anesthesia when given before surgery. Do not share this medicine with anyone else. Federal law prohibits the transfer of butorphanol to any person other than the patient for whom it was prescribed. Generic butorphanol injections are available.
What should my health care professional know before I receive butorphanol?
They need to know if you have any of these conditions:
- If you frequently drink alcohol-containing beverages
- constipation
- head injury
- heart disease
- intestinal disease, such as inflammatory bowel disease or ulcerative colitis
- liver disease
- lung disease, such as asthma or COPD
- kidney disease
- an allergic or unusual reaction to butorphanol, codeine, morphine, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
- breast-feeding
How should I use this medicine?
Butorphanol is for injection into a muscle or a vein. It is usually given by a health-care professional in a hospital or clinic setting.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?
This does not apply.
What drug(s) may interact with butorphanol?
Because butorphanol can cause drowsiness, other medicines that also cause drowsiness may increase this effect of butorphanol. Some medicines that cause drowsiness are:
- alcohol and alcohol-containing medicines
- barbiturates such as phenobarbital
- certain antidepressants, tranquilizers or medications for Parkinson's disease
- muscle relaxants
- certain antihistamines used in cold medicines
Ask your prescriber or health care professional about other medicines that may increase the effect of butorphanol.
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
Written and revised by
Gerald Hurowitz, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.

