Buprenorphine
Key points
- BUPRENORPHINE (Buprenexreg;) is used to treat moderate to severe pain, usually during or after surgery.
- Buprenorphine injection is usually given as injection into your vein or large muscle by a trained healthcare professional.
- You will receive doses of buprenorphine from your health care professional as you need them for pain.
- Because buprenorphine can cause drowsiness, other medicines that also cause drowsiness may increase this effect of buprenorphine.
Buprenorphine injection
What is Buprenorphine injection? BUPRENORPHINE (Buprenexreg;) is used to treat moderate to severe pain, usually during or after surgery. Generic buprenorphine injection is available.
What should my health care professional know before I receive Buprenorphine?
They need to know if you have any of these conditions:
- abnormal bladder function, difficulty urinating
- constipation
- enlarged prostate
- gallbladder disease
- if you frequently have alcohol-containing drinks
- intestinal disease, such as inflammatory bowel disease
- kidney disease
- liver disease
- lung disease, such as asthma or COPD
- an unusual reaction to buprenorphine, morphine, codeine, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
- breast-feeding
How should this medicine be used?
Buprenorphine injection is usually given as injection into your vein or large muscle by a trained healthcare professional.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?
This does not apply. You will receive doses of buprenorphine from your health care professional as you need them for pain.
What drug(s) may interact with Buprenorphine?
- amiodarone
- bosentan
- butorphanol
- clarithromycin
- entacapone
- erythromycin
- fluoxetine
- fluvoxamine
- levomethadyl
- medicines for fungal infections (examples: fluconazole, itraconazole, ketoconazole, voriconazole)
- medicines for seizures
- methadone
- mifepristone, RU-486
- nalbuphine
- naltrexone
- nefazodone
- pentazocine
- rifampin
Written and revised by
Gerald Hurowitz, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.

