Drug allergies

Key points
- Allergic reactions to drugs are fairly rare, but almost all drugs can cause a reaction of sorts in a small number of people.
- Drugs are routinely tested and scrutinised before they appear on the market.
- These are seen as mild reactions and can usually be treated by antihistamines, or by merely reducing or discontinuing the medication.
- Reactions can be either immediate or take a while to develop.
Allergic reactions to drugs are fairly rare, but almost all drugs can cause a reaction of sorts in a small number of people. Drug reactions ranging from a mild allergic reaction to a severe anaphylactic shock are possible.
Drugs are routinely tested and scrutinised before they appear on the market. If any significant number of the people on whom the drugs are tested, have an allergic reaction, the drug will not be released.
Some people are intolerant to drugs and may develop any of the following symptoms:
- Itching;
- Rashes or hives;
- Headaches;
- Nausea.
These are seen as mild reactions and can usually be treated by antihistamines, or by merely reducing or discontinuing the medication.
Reactions can be either immediate or take a while to develop. Previous exposure to the drug could mean increased severity of reaction every time the drug is used.
A far more severe reaction is called anaphylactic shock, which could be fatal. This happens very rarely, but if one develops any of the following symptoms, immediate medical attention is called for:
- All-over itchiness;
- Swelling of the face and ears;
- Constriction of the airway;
- Increased heart rate;
- Fainting.
The most common drug allergy is a reaction to drugs in the penicillin family. Other drugs that can trigger allergic reactions are sulphas, barbiturates, insulin, local anaesthetics and dyes injected into blood for X-ray purposes.
If a patient develops an allergy to medication, his GP must be alerted, he must wear a Medic Alert bracelet at all times and must get his GP to check routinely the contents of all prescription medication or over-the-counter medication.
Written and revised by
David Cohen, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.
Explore health topics
More in this topic
Lungs, Asthma & Allergies →
NewsOral drops can give kids needle-free relief from asthma, allergies
Allergy shots are commonly used to treat children with severe environmental allergies and asthma, but under-the-tongue drops may offer yet another beneficial - and stick-free - option for pediatric allergy sufferers,…
6 May 2013
NewsU.S.-born kids have more allergies, asthma
Kids and teens who are born abroad and immigrate to the United States are about half as likely to have asthma and allergies as those who are born in the U.S., according to a new study. Researchers surveyed the parents…
30 April 2013
NewsPeople with peanut/tree nut allergies can minimize risk of reactions on airplane flights
Few situations can provoke more anxiety for people with peanut or tree-nut allergies than having an allergic reaction while flying on an airplane and being unable to get help. But in a new study, published in the…


