Lomotil overdose

Alternative names

Diphenoxylate and Atropine

Definition

Poisoning from an overdose of Lomotil, an anti-diarrheal, which is a medication comprised of a narcotic agent (opoid derivative) and atropine.

Poisonous Ingredient

• diphenoxylate
  
• atropine
  

Where Found

• Lomotil
  
• Lofene
  
• Logen
  
• Lomanate
  
• Lonox
  

Note: This list may not be all inclusive.

Symptoms

• body as a whole
  o convulsions
  
• respiratory
  o slow breathing
  o stopped breathing
  
• eyes, ears, nose, and throat
  o pinpoint or dilated pupils
  o nystagmus (rapid side-to-side eye movements)
  
• skin
  o flushed skin
  
• gastrointestinal
  o constipation
  o nausea
  o vomiting
  o paralytic ileus
  
• heart and blood vessels
  o rapid heartbeat
  
• nervous system
  o drowsiness
  o coma
  o hallucinations
  

Note: Symptoms of toxicity may take up to 12 hours to appear.

Home Treatment

Call Poison Control.

Before Calling Emergency

Determine the following:

• the patient's age, weight, and condition
  
• the name of the product (ingredients and strengths if known)
  
• the time it was swallowed
  
• the amount swallowed
  
• it the medication was prescribed for the patient
  

Poison Control, or a local emergency number
They will instruct you if it is necessary to take the patient to the hospital. See Poison Control centers for telephone numbers and addresses. Take the container with you to the emergency room.

What to expect at the emergency room