Environmental tobacco smoke drastically increases an infant's risk for developing allergic rhinitis

University of Cincinnati (UC) epidemiologists say it's environmental tobacco smoke-not the suspected visible mold-that drastically increases an infant's risk for developing allergic rhinitis by age 1.

Commonly known as hay fever, allergic rhinitis occurs when a person's immune system mistakenly reacts to allergens (aggravating particles) in the air. The body then releases substances to protect itself, causing the allergy sufferer to experience persistent sneezing and a runny, blocked nose.

This is the first study to show a relationship between environmental tobacco smoke exposure and allergic rhinitis in year-old infants, the UC team reports in the June issue of Pediatric Allergy and Immunology and an early online edition May 17.

"Previous studies have addressed risk factors for allergic rhinitis, but they failed to examine multiple environmental exposures, and some yielded contradictory results," says Jocelyn Biagini, lead author and an epidemiologist in UC's environmental health department.

The study evaluated the effects of numerous indoor exposures to such things as environmental tobacco smoke, visible mold, pets, siblings and the day-care environment on 633 infants under age one.

"We found that infants who were exposed to 20 or more cigarettes a day were three times more likely to develop allergic rhinitis by their first birthday than those who were not exposed," says Biagini.

These findings, she says, suggest that for the health of their children, it's important for parents to eliminate tobacco smoke from their homes.

"An infant's lungs and immune system are still developing in the first year of life," says Grace LeMasters, PhD, coauthor and principal investigator of the Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS). "Environmental tobacco smoke puts harmful particulates in the air that-when inhaled regularly at such an early age-could lead to serious allergic conditions like asthma."

CCAAPS, funded by the National Institute of Environmental Health Sciences, is a five-year study examining the effects of environmental particulates on childhood respiratory health and allergy development.

About 43 percent of children, says Dr. LeMasters, are exposed to home environmental tobacco smoke. According to the Centers for Disease Control and Prevention, about 21 percent of all American adults smoke cigarettes. Of them, 12 percent report smoking 25 or more cigarettes daily.

While household mold, long thought to be a major cause, did not contribute to allergic rhinitis development, Biagini says, it did increase the infant's risk for ear infections.

Infants exposed to a mold patch about the size of a shoebox were five times more likely to contract ear infections requiring antibiotics than those living in mold-free homes, she explains.