Can Viagra relieve menstrual cramps?

Key points
- While many women find relief from menstrual cramps using over-the-counter ibuprofen, some suffer several days of debilitating pain every month without any relief from current treatments.
- In a very small clinical trial involving 25 women with severe menstrual cramps known as primary dysmenorrhea or PD, researchers found that a 100-milligram vaginal suppository of sildenafil citrate worked better than a placebo to relieve menstrual cramps over a four-hour time period.
- Previous research suggests that Viagra pills help relieve pelvic pain by dilating blood vessels.
- Those side effects weren’t seen in the new study, but larger trials are needed to determine the true safety and effectiveness of the suppository.
While many women find relief from menstrual cramps using over-the-counter ibuprofen, some suffer several days of debilitating pain every month without any relief from current treatments. That’s led researchers on a quest to find an improved method, and they’ve seen some promising results with the erectile dysfunction drug sildenafil citrate (Viagra).
In a very small clinical trial involving 25 women with severe menstrual cramps known as primary dysmenorrhea or PD, researchers found that a 100-milligram vaginal suppository of sildenafil citrate worked better than a placebo to relieve menstrual cramps over a four-hour time period. The study, published in the journal Human Reproduction, was supposed to include more than 60 patients but ended early due to a loss in funding from the National Institutes of Health.
Previous research suggests that Viagra pills help relieve pelvic pain by dilating blood vessels. But women also experienced more side effects, like headaches, which have made doctors reluctant to prescribe the pills.
Those side effects weren’t seen in the new study, but larger trials are needed to determine the true safety and effectiveness of the suppository.
“If future studies confirm these findings, sildenafil may become a treatment option for patients with PD,” said study co-author Dr. Richard Legro, a professor of obstetrics and gynecology and public health sciences at Penn State.
Menstrual cramps, also known as dysmenorrhea or period pains, are painful sensations felt in the lower abdomen that can occur both before and during a woman's menstrual period. The pain ranges from dull and annoying to severe and extreme. Menstrual cramps tend to begin after an egg is released from the ovaries and travels down the fallopian tube (ovulation).
There are two primary types of these difficult or painful periods - primary and secondary dysmenorrhea:
Primary dysmenorrhea is the most common type and is characterized by pain in the lower abdomen and lower back pain beginning 1-2 days before the period and lasting from 2 to 4 days. There is no underlying problem that is causing the pain
Secondary dysmenorrhea is characterized by cramping pains that are due to an identifiable medical problem such as endometriosis, uterine fibroids, or pelvic inflammatory disease.
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Deborah Kotz can be reached at [email protected]. -
Written and revised by
Gerald Hurowitz, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.
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