Shorter sleep may speed brain aging

Key points
- With less sleep, normal aging-related structural changes in the brain progress slightly faster in middle-aged and older people, according to a new brain imaging study.
- The mind and body benefits of a solid night’s sleep are undeniable, yet science is just now beginning to understand precisely why this activity is so essential when it comes to learning and memory formation.
- To investigate the contribution of sleep duration and quality to age-related changes in brain structure and cognitive performance in relatively healthy older adults.
- In healthy older adults, short sleep duration is associated with greater age-related brain atrophy and cognitive decline.
With less sleep, normal aging-related structural changes in the brain progress slightly faster in middle-aged and older people, according to a new brain imaging study.
Sleep troubles are more common with age, and shrinkage of certain brain structures is normal. But for the over-55 study participants, those changes could be seen accelerating slightly with each hour less of sleep each night.
“Among older adults, sleeping less will increase the rate their brain ages and speed up the decline in their cognitive functions,” said lead study author Dr. June Lo, a researcher with Duke-NUS Graduate Medical School in Singapore.
Plenty of past research has shown that lack of sleep can worsen fuzzy thinking and memory problems in the short term, and at all ages, Lo and her colleagues note in the journal Sleep.
“Our lab has also shown repeatedly in the past decade that in young adults, brain and cognitive functions are affected when people do not have enough sleep,” she told Reuters Health in an email. “As a result, we wanted to know whether sleeping less would affect brain and cognitive aging in older adults.”
Fewer studies have looked at physical changes in the brain and their link to sleep over time, the report points out. And none have done it for older adults, according to the researchers.
To assess the effects of sleep duration on both thinking and brain structure, the study team analyzed data on healthy people over age 55 participating in the larger Singapore Longitudinal Aging Brain Study.
Lo and her colleagues looked at data on 66 Chinese adults who had previously undergone magnetic resonance imaging (MRI) scans to measure brain volume in specific areas and had taken tests to assess their cognitive skills.
The researchers used questionnaires to determine participants’ sleep duration and quality, and measured blood levels of high sensitivity C-reactive protein, an indicator of inflammation.
When the cognitive tests and scans were repeated two years after the initial round, the researchers found those participants who slept fewer hours showed evidence of faster brain shrinkage and declines in cognitive performance.
In our 20s and 30s, our brains begin to change in ways that affect how we store memories. We become more forgetful. If you're in your 40s and 50s, you might worry that forgetfulness is an early sign of Alzheimer's disease. But, not all forgetfulness is serious. For instance, knowing a word and not being able to remember it is usually a temporary problem. It's common to forget some of the many things you need to do. And many people mix up, or even forget, appointments now and then. Use lists and a calendar to keep you on track. Put things like your keys in the same place every time.
Just as physical activity keeps your body strong, mental activity can help keep your mind engaged and challenged as you age. Some research suggests that activities that engage your brain might offer some protection against cognitive decline. Here are some activities you might try:
Written and revised by
Gerald Hurowitz, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.
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