Chemicals in plastics and cosmetics tied to early births

Chemicals called phthalates, found in plastics and cosmetics, may be linked to a raised risk of babies being born early, suggests a new study.

Researchers found that women who delivered babies before 37 weeks gestation had higher levels of phthalates in their urine, compared to women who delivered their children at full term, which is 39 weeks.

"Preterm birth is a real public health problem," said John Meeker, who led the study. "We're not really sure how to go about preventing it, but this may shed light on environmental factors that people may want to be educated in."

Meeker, from the University of Michigan School of Public Health in Ann Arbor, added, "We knew that exposure to phthalates was virtually ubiquitous here in the U.S. and possibly worldwide and preterm births increased for unknown reasons over the past several decades."

Phthalates are included in products for a variety of reasons, include to make plastic flexible.

Past studies also have found evidence that would suggest the chemicals may be tied to earlier births.

For example, previous research has linked the chemicals to shorter pregnancies and lower birth weights.

"There are many possible routes of exposure depending on the chemical of interest and the scenario," Meeker said. Most commonly, the chemical enters the body through food and beverages. It may also be absorbed through the skin.

For the new study, the researchers used data from a study conducted at Brigham and Women's Hospital in Boston between 2006 and 2008.

During the study, pregnant women were asked to fill out surveys and provide urine samples throughout their pregnancies. The researchers compared 130 mothers who delivered their babies before 37 weeks to 352 women who delivered their babies at term.

While each woman provided numerous urine samples during their pregnancies, the researchers analyzed three to measure the amount of phthalates in their bodies.

They looked for breakdown products of a phthalate chemical known as DEHP.

Overall, the two byproducts MEHP and MECPP were more abundant in women who delivered their children early, compared to women who delivered after 37 weeks. That was also true for MBP, a byproduct of Dibutyk phthalate.

According to the U.S. Environmental Protection Agency, those chemicals are used to make products - such as plastic pipes, shower curtains and food packaging - soft and flexible.

Each of the phthalates examined was linked to a risk increase of anywhere from 16 percent to 65 percent increase in risk for preterm birth.

About one of every eight infants is born prematurely in the U.S., according to the Centers for Disease Control and Prevention.

Shanna Swan, who wrote an editorial accompanying the new study in JAMA Pediatrics, said that difference may not mean much to an individual woman, but it adds up across a large population.