Ectopic Pregnancy Clinical Findings

Key points
- No specific symptoms or signs are pathognomonic for ectopic pregnancy, and many disorders can present similarly.
- The following symptoms may assist in the diagnosis of ectopic pregnancy.
- On examination, the following signs are important in the diagnosis of ectopic gestation.
- Hematocrit: The hematocrit will vary depending on the patient population and the degree, if any, of intraabdominal bleeding.
No specific symptoms or signs are pathognomonic for ectopic pregnancy, and many disorders can present similarly. Normal pregnancy, threatened or incomplete abortion, rupture of an ovarian cyst, ovarian torsion, gastroenteritis, and appendicitis can all be confused with ectopic pregnancy. Since early diagnosis is crucial, a high index of suspicion should be maintained when any pregnant woman in the first trimester presents with bleeding and/or abdominal pain. Fifteen to twenty percent of ectopic gestations will present as surgical emergencies.
A. Symptoms
The following symptoms may assist in the diagnosis of ectopic pregnancy.
1. Pain - Pelvic or abdominal pain is present in close to 100% of cases. Pain can be unilateral or bilateral, localized or generalized. The presence of subdiaphragmatic or shoulder pain is more variable, depending on the amount of intraabdominal bleeding.
2. Bleeding - Abnormal uterine bleeding, usually spotting, occurs in roughly 75% of cases, and represents decidual sloughing.
3. Amenorrhea - Secondary amenorrhea is variable. Approximately half of women with ectopic pregnancies have some spotting at the time of their expected menses, and thus do not realize they are pregnant.
4. Syncope - Dizziness, lightheadedness, and/or syncope is present in one-third to one-half of cases.
5. Decidual cast - A decidual cast is passed in 5-10% of ectopic pregnancies, and may be mistaken for products of conception.
B. Signs
On examination, the following signs are important in the diagnosis of ectopic gestation.
1. Tenderness - Diffuse or localized abdominal tenderness is present in over 80% of ectopic pregnancies. Adnexal and/or cervical motion tenderness is present in over 75% of cases.
2. Adnexal mass - A unilateral adnexal mass is palpated in one-third to one-half of patients. Occasionally, a cul-de-sac mass is present. However, the patient's discomfort may preclude an adequate examination.
3. Uterine changes - The uterus may undergo typical changes of pregnancy, including softening and a slight increase in size.
Laboratory Findings
Hematocrit: The hematocrit will vary depending on the patient population and the degree, if any, of intraabdominal bleeding.
White blood count: The white blood count is variable, and it is not uncommon to see a leukocytosis.
Written and revised by
David Cohen, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.
Explore health topics
More in this topic
Pregnancy & Fertility →
NewsLatest study looks at alternative therapies to prevent malaria in pregnancy
Researchers at LSTM, working with colleagues of the Centres for Disease Control and Prevention (CDC) in Kenya and USA, and from the Kenya Medical Research Institution have found that a new drug may be more effective at…
30 September 2015
NewsNew studies show no long term effects of antidepressant use during pregnancy
The use of antidepressants during pregnancy has no long term neurodevelopmental or behavioural effects on the child, however they may be associated with an increased risk of postpartum haemorrhage, suggests the findings…
17 September 2015
NewsHealthy Diet Before Pregnancy: Good for Baby's Heart?
Better maternal diet in the year prior to conception was associated with lower risk of serious congenital heart defects, according to the results of a large retrospective case-control analysis using data from the…





